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Atf7ip2 activating transcription factor 7 interacting protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497859, updated on 3-Jun-2026
Official Symbol
Atf7ip2provided by RGD
Official Full Name
activating transcription factor 7 interacting protein 2provided by RGD
Primary source
RGD:1583744
See related
Ensembl:ENSRNOG00000025522 AllianceGenome:RGD:1583744
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human ATF7IP2 (activating transcription factor 7 interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Testes (RPKM 23.4), Kidney (RPKM 3.9) and 2 other tissues See more
Orthologs
all
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See Atf7ip2 in Genome Data Viewer
Location:
10q11
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (5909898..5952844, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (5403099..5445989, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (5476205..5519893, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tektin 5 Neighboring gene epithelial membrane protein 2 Neighboring gene uncharacterized LOC134480748 Neighboring gene ribosomal protein L39 like 1 Neighboring gene uncharacterized LOC108352053

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
activating transcription factor 7-interacting protein 2

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017471.1 → NP_001017471.1  activating transcription factor 7-interacting protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001017471.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083663
    UniProtKB/TrEMBL
    F7EMW9, Q5XIL7
    Related
    ENSRNOP00000032259.5, ENSRNOT00000039429.6
    Conserved Domains (1) summary
    pfam16788
    Location:59 → 262
    ATF7IP_BD; ATF-interacting protein binding domain

  2. NM_001438430.1 → NP_001425359.1  activating transcription factor 7-interacting protein 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I5ZM83

  3. NM_001438432.1 → NP_001425361.1  activating transcription factor 7-interacting protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

  4. NM_001438433.1 → NP_001425362.1  activating transcription factor 7-interacting protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    5909898..5952844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008767495.4 → XP_008765717.1  

    Conserved Domains (1) summary
    pfam16788
    Location:70 → 273
    ATF7IP_BD; ATF-interacting protein binding domain

  2. XM_006245728.5 → XP_006245790.1  

    Related
    ENSRNOP00000079052.1, ENSRNOT00000109058.2
    Conserved Domains (2) summary
    pfam16788
    Location:70 → 273
    ATF7IP_BD; ATF-interacting protein binding domain
    pfam16794
    Location:353 → 451
    fn3_4; Fibronectin-III type domain

  3. XM_006245732.5 → XP_006245794.1  

    Conserved Domains (2) summary
    pfam16788
    Location:59 → 262
    ATF7IP_BD; ATF-interacting protein binding domain
    pfam16794
    Location:342 → 440
    fn3_4; Fibronectin-III type domain

  4. XM_008767496.4 → XP_008765718.1  activating transcription factor 7-interacting protein 2 isoform X4

    UniProtKB/TrEMBL
    A6K4K8
    Conserved Domains (1) summary
    pfam16788
    Location:70 → 273
    ATF7IP_BD; ATF-interacting protein binding domain

RNA

  1. XR_005489903.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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