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OMP olfactory marker protein [ Homo sapiens (human) ]

Gene ID: 4975, updated on 25-Nov-2021

Summary

Official Symbol
OMPprovided by HGNC
Official Full Name
olfactory marker proteinprovided by HGNC
Primary source
HGNC:HGNC:8136
See related
Ensembl:ENSG00000254550 MIM:164340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OMP in Genome Data Viewer
Location:
11q13.5
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (77102840..77103331)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (76813886..76814377)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369399 Neighboring gene uncharacterized LOC105369400 Neighboring gene calpain 5 Neighboring gene myosin VIIA Neighboring gene glycerophosphodiester phosphodiesterase domain containing 4

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables peptide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chemical synaptic transmission TAS
Traceable Author Statement
more info
PubMed 
involved_in neurogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory marker protein
Names
olfactory neuronal-specific protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006189.1NP_006180.1  olfactory marker protein

    See identical proteins and their annotated locations for NP_006180.1

    Status: REVIEWED

    Source sequence(s)
    AP000752
    Consensus CDS
    CCDS53682.1
    UniProtKB/Swiss-Prot
    P47874
    Related
    ENSP00000436376.1, ENST00000529803.1
    Conserved Domains (1) summary
    pfam06554
    Location:11161
    Olfactory_mark; Olfactory marker protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    77102840..77103331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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