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BDNF-AS BDNF antisense RNA [ Homo sapiens (human) ]

Gene ID: 497258, updated on 11-Jun-2021

Summary

Official Symbol
BDNF-ASprovided by HGNC
Official Full Name
BDNF antisense RNAprovided by HGNC
Primary source
HGNC:HGNC:20608
See related
Ensembl:ENSG00000245573 MIM:611468
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BDNF; BDNFAS; BDNFOS; BDNF-AS1; ANTI-BDNF; NCRNA00049
Expression
Ubiquitous expression in brain (RPKM 3.5), thyroid (RPKM 1.9) and 23 other tissues See more
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Genomic context

See BDNF-AS in Genome Data Viewer
Location:
11p14.1
Exon count:
10
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (27506852..27698171)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (27528399..27719718)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37a pseudogene 7 Neighboring gene lin-7 homolog C, crumbs cell polarity complex component Neighboring gene RNA, 5S ribosomal pseudogene 339 Neighboring gene microRNA 8087 Neighboring gene ribosomal protein S25 pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 678 Neighboring gene Sharpr-MPRA regulatory region 8127 Neighboring gene brain derived neurotrophic factor Neighboring gene chromobox 3 pseudogene 1 Neighboring gene heat shock protein 90 alpha family class A member 2, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome wide association study identifies KCNMA1 contributing to human obesity.
GeneReviews: Not available
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
GeneReviews: Not available
Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
GeneReviews: Not available
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
GeneReviews: Not available
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • BDNF antisense RNA (non-protein coding)
  • BDNF antisense RNA 1 (non-protein coding)
  • BDNF opposite strand (non-protein coding)
  • brain-derived neurotrophic factor opposite strand

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002832.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (BT2B) represents the longest transcript.
    Source sequence(s)
    AC100771, AC104563, KF459669
    Related
    ENST00000499008.8
  2. NR_033312.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (BT1C) lacks an alternate exon and uses an alternate 3' splice pattern, compared to variant BT2B.
    Source sequence(s)
    AC100771, AC104563, KF459669
    Related
    ENST00000499568.3
  3. NR_033313.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (BT1A) lacks an alternate exon and uses an alternate 3' splice pattern, compared to variant BT2B.
    Source sequence(s)
    AC100771, AC104563, KF459669
    Related
    ENST00000502161.7
  4. NR_033314.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (BT2A) lacks an alternate exon, compared to variant BT2B.
    Source sequence(s)
    AC100771, AC104563, KF459669
    Related
    ENST00000651193.1
  5. NR_033315.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (BT1B) lacks two alternate exons and uses an alternate 3' splice pattern, compared to variant BT2B.
    Source sequence(s)
    AC100771, AC104563, KF459669
    Related
    ENST00000500662.7

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    27506852..27698171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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