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CLEC18B C-type lectin domain family 18 member B [ Homo sapiens (human) ]

Gene ID: 497190, updated on 11-Jun-2021

Summary

Official Symbol
CLEC18Bprovided by HGNC
Official Full Name
C-type lectin domain family 18 member Bprovided by HGNC
Primary source
HGNC:HGNC:33849
See related
Ensembl:ENSG00000140839 MIM:616572
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MRCL2
Expression
Biased expression in kidney (RPKM 34.8) and testis (RPKM 8.2) See more
Orthologs
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Genomic context

See CLEC18B in Genome Data Viewer
Location:
16q23.1
Exon count:
16
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (74408631..74422248, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (74442529..74456039, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene nuclear pore complex interacting protein family member B15 Neighboring gene uncharacterized LOC105376772 Neighboring gene uncharacterized LOC107984827 Neighboring gene RNA, U6 small nuclear 237, pseudogene Neighboring gene golgi glycoprotein 1 Neighboring gene ribosomal protein S10 pseudogene 23

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables polysaccharide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus TAS
Traceable Author Statement
more info
PubMed 
located_in endosome TAS
Traceable Author Statement
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in sarcoplasmic reticulum TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
C-type lectin domain family 18 member B
Names
mannose receptor-like 2
mannose receptor-like protein 1
secretory protein LOC497190

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011880.3NP_001011880.2  C-type lectin domain family 18 member B isoform 2 precursor

    See identical proteins and their annotated locations for NP_001011880.2

    Status: VALIDATED

    Source sequence(s)
    AY358373, BM695392, DA374548, DA375446, DC309733
    Consensus CDS
    CCDS32484.1
    UniProtKB/Swiss-Prot
    Q6UXF7
    Related
    ENSP00000341051.5, ENST00000339953.9
    Conserved Domains (2) summary
    cd00037
    Location:310443
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cd05380
    Location:50183
    SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...
  2. NM_001385192.1NP_001372121.1  C-type lectin domain family 18 member B isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC009053
    Related
    ENSP00000483587.1, ENST00000619275.4
    Conserved Domains (2) summary
    cd00037
    Location:310434
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cd05380
    Location:50183
    CAP_euk; Eukaryotic CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins
  3. NM_001385193.1NP_001372122.1  C-type lectin domain family 18 member B isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC009053
    Related
    ENSP00000507367.1, ENST00000682950.1
    Conserved Domains (2) summary
    cd00037
    Location:310434
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cd05380
    Location:50183
    CAP_euk; Eukaryotic CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins
  4. NM_001385194.1NP_001372123.1  C-type lectin domain family 18 member B isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC009053
    Conserved Domains (2) summary
    cd00037
    Location:230354
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl00133
    Location:73109
    CAP; CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family
  5. NM_001385195.1NP_001372124.1  C-type lectin domain family 18 member B isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC009053
    Conserved Domains (2) summary
    cd00037
    Location:230354
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl00133
    Location:73109
    CAP; CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    74408631..74422248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002957807.1 RNA Sequence

    Related
    ENST00000620745.1
  2. XR_001751905.1 RNA Sequence

  3. XR_002957808.1 RNA Sequence

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