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Rnase13 ribonuclease, RNase A family, 13 (non-active) [ Mus musculus (house mouse) ]

Gene ID: 497071, updated on 9-Mar-2023

Summary

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Official Symbol
Rnase13provided by MGI
Official Full Name
ribonuclease, RNase A family, 13 (non-active)provided by MGI
Primary source
MGI:MGI:3528592
See related
Ensembl:ENSMUSG00000068392 AllianceGenome:MGI:3528592
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable nucleic acid binding activity. Predicted to be located in extracellular region. Orthologous to human RNASE13 (ribonuclease A family member 13 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 122.4) See more
Orthologs
human all
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Genomic context

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See Rnase13 in Genome Data Viewer
Location:
14; 14 C2
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (52158822..52160734, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (51921365..51923277, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene N-myc downstream regulated gene 2 Neighboring gene tubulin polymerization-promoting protein family member 2 Neighboring gene chaperonin containing Tcp1, subunit 6a (zeta) pseudogene Neighboring gene Rho guanine nucleotide exchange factor (GEF) 40 Neighboring gene predicted gene, 16617

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice. Noda T, et al. Andrology, 2019 Sep. PMID 30927342, Free PMC Article
  2. The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. Cho S, et al. Genomics, 2005 Feb. PMID 15676279
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NOT enables RNA nuclease activity IKR
Inferred from Key Residues
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable inactive ribonuclease-like protein 13
Names
pancreatic ribonuclease
ribonuclease-like protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011687.3 → NP_001011687.1  probable inactive ribonuclease-like protein 13 precursor

    See identical proteins and their annotated locations for NP_001011687.1

    Status: VALIDATED

    Source sequence(s)
    AC125087
    Consensus CDS
    CCDS27048.1
    UniProtKB/Swiss-Prot
    Q5GAM7
    Related
    ENSMUSP00000087203.3, ENSMUST00000089771.4
    Conserved Domains (1) summary
    pfam00074
    Location:27 → 150
    RnaseA; Pancreatic ribonuclease

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    52158822..52160734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519219.2 → XP_006519282.1  probable inactive ribonuclease-like protein 13 isoform X1

    UniProtKB/Swiss-Prot
    Q5GAM7
    Conserved Domains (1) summary
    pfam00074
    Location:27 → 150
    RnaseA; Pancreatic ribonuclease

  2. XM_006519218.1 → XP_006519281.1  probable inactive ribonuclease-like protein 13 isoform X1

    See identical proteins and their annotated locations for XP_006519281.1

    UniProtKB/Swiss-Prot
    Q5GAM7
    Conserved Domains (1) summary
    pfam00074
    Location:27 → 150
    RnaseA; Pancreatic ribonuclease

  3. XM_017316076.2 → XP_017171565.1  probable inactive ribonuclease-like protein 13 isoform X1

    UniProtKB/Swiss-Prot
    Q5GAM7
    Conserved Domains (1) summary
    pfam00074
    Location:27 → 150
    RnaseA; Pancreatic ribonuclease
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5GAM7.1 GenPept UniProtKB/Swiss-Prot:Q5GAM7

Gene LinkOut

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