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prim2.S DNA primase subunit 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 496363, updated on 4-Jan-2025

Summary

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Official Symbol
prim2.S
Official Full Name
DNA primase subunit 2 S homeolog
Primary source
Xenbase:XB-GENE-1004025
Locus tag
XELAEV_18029485mg
See related
EnsemblRapid:ENSXLAG00005027981 AllianceGenome:Xenbase:XB-GENE-1004025
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
p58; prim2; prim2a; prim2.L
Summary
Predicted to enable 4 iron, 4 sulfur cluster binding activity; DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within DNA replication, synthesis of primer. Predicted to be part of alpha DNA polymerase:primase complex. Orthologous to human PRIM2 (DNA primase subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See prim2.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (81690803..81744029, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (77051907..77104661, complement)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene KH domain containing, RNA binding, signal transduction associated 2 S homeolog Neighboring gene uncharacterized LOC121394256 Neighboring gene RAB23, member RAS oncogene family S homeolog Neighboring gene BAG cochaperone 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA replication, synthesis of primer IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of alpha DNA polymerase:primase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA primase large subunit
Names
DNA primase subunit 2) L homeolog
primase, DNA, polypeptide 2 (58kDa) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    81690803..81744029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018265526.2 → XP_018121015.1  DNA primase large subunit

    UniProtKB/TrEMBL
    A0A1L8G3G3, A0A974HHL3, Q5HZL6
    Related
    ENSXLAP00005083386.1, ENSXLAT00005085024.1
Nucleotide Protein Strain
Heading Accession and Version

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