U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hrg hiiragi [ Drosophila melanogaster (fruit fly) ]

Gene ID: 49636, updated on 19-Jun-2024

Summary

Official Symbol
hrgprovided by FlyBase
Official Full Name
hiiragiprovided by FlyBase
Primary source
FLYBASE:FBgn0015949
Locus tag
Dmel_CG9854
See related
AllianceGenome:FB:FBgn0015949
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9854; dHrg; Dmel\CG9854; Hiiragi; l(2)07619; l(2)k07619; Pap; PAP
Summary
Enables polynucleotide adenylyltransferase activity. Predicted to be involved in mRNA polyadenylation. Is expressed in several structures, including embryonic brain; embryonic/larval midgut; epithelium; gonad; and larval ventral nerve cord. Orthologous to several human genes including PAPOLA (poly(A) polymerase alpha). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See hrg in Genome Data Viewer
Location:
56E1-56E1; 2-90 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19663919..19669832, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15551424..15557337, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44504 Neighboring gene mir-309 stem loop Neighboring gene uncharacterized protein Neighboring gene Kip1 ubiquitination-promoting complex subunit 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables poly(A) RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(A) RNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables poly(A) RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
enables poly(A) RNA polymerase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in RNA 3'-end processing IEA
Inferred from Electronic Annotation
more info
 
involved_in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cytosolic mRNA polyadenylation IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hiiragi
Names
CG9854-PA
CG9854-PB
CG9854-PC
CG9854-PD
Poly(A) polymerase
hrg-PA
hrg-PB
hrg-PC
hrg-PD
poly (A) polymerase
NP_001036562.1
NP_001261097.1
NP_536790.1
NP_725919.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    19663919..19669832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080529.4NP_536790.1  hiiragi, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_536790.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MZ09, Q9N6D7
    Related
    FBpp0085678
    Conserved Domains (3) summary
    PTZ00418
    Location:28600
    PTZ00418; Poly(A) polymerase; Provisional
    pfam04926
    Location:374534
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:29371
    PAP_central; Poly(A) polymerase central domain
  2. NM_001274168.2NP_001261097.1  hiiragi, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261097.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KG96
    Conserved Domains (3) summary
    PTZ00418
    Location:28600
    PTZ00418; Poly(A) polymerase; Provisional
    pfam04926
    Location:374534
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:29371
    PAP_central; Poly(A) polymerase central domain
  3. NM_166372.3NP_725919.1  hiiragi, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725919.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MZ09, Q9N6D7
    Related
    FBpp0085679
    Conserved Domains (3) summary
    PTZ00418
    Location:28600
    PTZ00418; Poly(A) polymerase; Provisional
    pfam04926
    Location:374534
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:29371
    PAP_central; Poly(A) polymerase central domain
  4. NM_001043097.3NP_001036562.1  hiiragi, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036562.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MZ09, Q9N6D7
    Conserved Domains (3) summary
    PTZ00418
    Location:28600
    PTZ00418; Poly(A) polymerase; Provisional
    pfam04926
    Location:374534
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:29371
    PAP_central; Poly(A) polymerase central domain