U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ORF64 ORF64 [ Human gammaherpesvirus 8 ]

Gene ID: 4961441, updated on 18-Aug-2023
Gene symbol
ORF64
Gene description
ORF64
Locus tag
HHV8GK18_gp72
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Human gammaherpesvirus 8 (strain: GK18, type: P, common: Kaposi's sarcoma-associated herpesvirus, acronym: HHV-8, acronym: KSHV, nat-host: Homo sapiens)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_009333.1 (104106..112013)

NC_009333.1Genomic Context describing neighboring genes Neighboring gene vIRF-2 Neighboring gene ORF58 Neighboring gene ORF60 Neighboring gene ORF61 Neighboring gene ORF59 Neighboring gene ORF62 Neighboring gene ORF63 Neighboring gene ORF67A Neighboring gene ORF65 Neighboring gene ORF66 Neighboring gene ORF67 Neighboring gene ORF68 Neighboring gene ORF69 Neighboring gene K12

Genomic Sequence:
NC_009333.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Inhibition of RIG-I-mediated signaling by Kaposi's sarcoma-associated herpesvirus-encoded deubiquitinase ORF64. Inn KS, et al. J Virol, 2011 Oct. PMID 21835791, Free PMC Article
  2. Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1. Gastaldello S, et al. J Mol Cell Biol, 2012 Aug. PMID 22474075
  3. Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome. Gupta S, et al. PLoS Pathog, 2018 Jan. PMID 29357390, Free PMC Article
  4. Kaposi's sarcoma-associated herpesvirus immune modulation: an overview. Rezaee SAR, et al. J Gen Virol, 2006 Jul. PMID 16760382

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

regulatory

  • Loc: 111992-111997 regulatory_class = polyA_signal_sequence
Preferred Names
ORF64
YP_001129421.1
  • herpesvirus core gene UL36 family

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_009333.1 Reference assembly

    Range
    104106..112013
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001129421.1 ORF64 [Human gammaherpesvirus 8]

    See identical proteins and their annotated locations for YP_001129421.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q2HR64
    UniProtKB/TrEMBL
    A0A7D3QGU7, A0A7D5FQZ2, A0A7D5JP69, D0UZT1, K0FHU5, O40942, P88955
    Conserved Domains (3) summary
    TIGR00618
    Location:1385 → 1646
    sbcc; exonuclease SbcC
    PHA03247
    Location:2164 → 2484
    PHA03247; large tegument protein UL36; Provisional
    pfam04843
    Location:13 → 186
    Herpes_teg_N; Herpesvirus tegument protein, N-terminal conserved region
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.