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rtraf.L RNA transcription, translation and transport factor L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 494815, updated on 5-Sep-2025
Official Symbol
rtraf.L
Official Full Name
RNA transcription, translation and transport factor L homeolog
Primary source
Xenbase:XB-GENE-17334024
Locus tag
XELAEV_18039668mg
See related
EnsemblRapid:ENSXLAG00005019458 AllianceGenome:Xenbase:XB-GENE-17334024
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rtraf; lcrp369; c14orf166; c14orf166.L
Summary
Predicted to enable RNA binding activity and RNA polymerase II complex binding activity. Predicted to act upstream of or within negative regulation of protein kinase activity; positive regulation of transcription by RNA polymerase II; and tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be located in microtubule cytoskeleton; nucleus; and perinuclear region of cytoplasm. Predicted to be part of tRNA-splicing ligase complex. Orthologous to human RTRAF (RNA transcription, translation and transport factor). [provided by Alliance of Genome Resources, Jul 2025]
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See rtraf.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (86763509..86776244, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (72083428..72096257, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene prostaglandin E receptor 2 L homeolog Neighboring gene nidogen 2 L homeolog Neighboring gene guanine nucleotide binding protein (G protein), gamma 2 L homeolog Neighboring gene FERM domain containing 6 L homeolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  2. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II complex binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of protein kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within tRNA splicing, via endonucleolytic cleavage and ligation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in mitotic spindle ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of tRNA-splicing ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
  
Preferred Names
RNA transcription, translation and transport factor protein
Names
UPF0568 protein C14orf166 homolog

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094644.1 → NP_001088113.1  RNA transcription, translation and transport factor protein

    See identical proteins and their annotated locations for NP_001088113.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082840
    UniProtKB/Swiss-Prot
    Q63ZS0
    UniProtKB/TrEMBL
    A0A974C2A0, A0A974C812
    Related
    ENSXLAP00005057136.1, ENSXLAT00005058483.1
    Conserved Domains (1) summary
    pfam10036
    Location:5 → 239
    RLL; Putative carnitine deficiency-associated protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    86763509..86776244 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q63ZS0.1 GenPept UniProtKB/Swiss-Prot:Q63ZS0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials