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Gsta5 glutathione S-transferase alpha 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 494499, updated on 10-Oct-2019

Summary

Official Symbol
Gsta5provided by RGD
Official Full Name
glutathione S-transferase alpha 5provided by RGD
Primary source
RGD:1593189
See related
Ensembl:ENSRNOG00000000201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gsta2
Expression
Biased expression in Liver (RPKM 6559.5), Kidney (RPKM 3991.1) and 1 other tissue See more

Genomic context

See Gsta5 in Genome Data Viewer
Location:
8q31
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (85553659..85564914)
106 current Rn_Celera (GCF_000002265.2) 8 AC_000076.1 (78852562..78862243)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (85111369..85122622)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554755 Neighboring gene glutathione S-transferase alpha 4 Neighboring gene glutathione S-transferase alpha 4 pseudogene Neighboring gene similar to glyceraldehyde-3-phosphate dehydrogenase Neighboring gene glutathione S-transferase alpha 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC114217

Gene Ontology Provided by RGD

Function Evidence Code Pubs
glutathione binding IDA
Inferred from Direct Assay
more info
PubMed 
glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutathione transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to bacterium ISO
Inferred from Sequence Orthology
more info
PubMed 
response to stilbenoid ISO
Inferred from Sequence Orthology
more info
PubMed 
xenobiotic catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
xenobiotic metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glutathione S-transferase alpha-2
Names
GHS transferase
GST 1b-1b
GST A2-2
GST Ya2
glutathione S-transferase Ya subunit
glutathione S-transferase Ya-2
glutathione transferase YA subunit
NP_001010921.1
XP_017451300.1
XP_017451301.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010921.1NP_001010921.1  glutathione S-transferase alpha-2

    See identical proteins and their annotated locations for NP_001010921.1

    Status: VALIDATED

    Source sequence(s)
    CO566028, K00136
    UniProtKB/Swiss-Prot
    P04903
    UniProtKB/TrEMBL
    Q4FZZ3
    Conserved Domains (3) summary
    PTZ00057
    Location:1208
    PTZ00057; glutathione s-transferase; Provisional
    cd03208
    Location:86220
    GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    cd03077
    Location:482
    GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    85553659..85564914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017595811.1XP_017451300.1  glutathione S-transferase alpha-2 isoform X1

    UniProtKB/TrEMBL
    Q4FZZ3
    Related
    ENSRNOP00000043510.4, ENSRNOT00000044944.5
    Conserved Domains (3) summary
    PTZ00057
    Location:1208
    PTZ00057; glutathione s-transferase; Provisional
    cd03208
    Location:86220
    GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    cd03077
    Location:482
    GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...
  2. XM_017595812.1XP_017451301.1  glutathione S-transferase alpha-2 isoform X1

    UniProtKB/TrEMBL
    Q4FZZ3
    Conserved Domains (3) summary
    PTZ00057
    Location:1208
    PTZ00057; glutathione s-transferase; Provisional
    cd03208
    Location:86220
    GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    cd03077
    Location:482
    GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    78852562..78862243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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