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tfr1a transferrin receptor 1a [ Danio rerio (zebrafish) ]

Gene ID: 494477, updated on 3-Oct-2019

Summary

Official Symbol
tfr1aprovided by ZNC
Official Full Name
transferrin receptor 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041220-1
See related
Ensembl:ENSDARG00000101322
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Orthologs

Genomic context

See tfr1a in Genome Data Viewer
Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (4844080..4874960, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (5008255..5034268, complement)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (4737318..4763696, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886376 Neighboring gene teleost multiple tissue opsin a Neighboring gene tyrosine kinase, non-receptor, 2b Neighboring gene si:ch211-162e15.3 Neighboring gene discs, large (Drosophila) homolog 1, like

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
transferrin receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular iron ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
cellular iron ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
hemoglobin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
iron ion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
 
transferrin transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transferrin receptor protein 1
Names
chianti
cia

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009917.1NP_001009917.1  transferrin receptor protein 1

    See identical proteins and their annotated locations for NP_001009917.1

    Status: PROVISIONAL

    Source sequence(s)
    AY649363
    UniProtKB/TrEMBL
    Q5MPX4
    Related
    ENSDARP00000150808.1, ENSDART00000189835.1
    Conserved Domains (3) summary
    cd09848
    Location:384615
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:203376
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:652760
    TFR_dimer; Transferrin receptor-like dimerization domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    4844080..4874960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163666.4XP_005163723.1  transferrin receptor protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005163723.1

    UniProtKB/TrEMBL
    Q5MPX4
    Related
    ENSDARP00000137503.1, ENSDART00000165296.2
    Conserved Domains (3) summary
    cd09848
    Location:384615
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:203376
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:652760
    TFR_dimer; Transferrin receptor-like dimerization domain
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