cdk11b cyclin dependent kinase 11B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cdk11bprovided by ZNC
Official Full Name: cyclin dependent kinase 11Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041212-74
See related: Ensembl:ENSDARG00000102546 AllianceGenome:ZFIN:ZDB-GENE-041212-74
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cdc2l1; im:7142267; zgc:101589
Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within smoothened signaling pathway. Predicted to be active in nucleus. Orthologous to human CDK11B (cyclin dependent kinase 11B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (53948192..53960411, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (53615204..53627412, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables cyclin-dependent protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in protein phosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within smoothened signaling pathway	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cyclin-dependent kinase 11B; cell division protein kinase 11

Names: cell division cycle 2-like 1 (PITSLRE proteins)

NP_001008646.1

EC 2.7.11.22

XP_009302607.1

EC 2.7.11.22

XP_009302610.1

EC 2.7.11.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008646.1 → NP_001008646.1 cyclin-dependent kinase 11B

See identical proteins and their annotated locations for NP_001008646.1

Status: PROVISIONAL

Source sequence(s)

BC086709

UniProtKB/TrEMBL

Q5PRD1

Related

ENSDARP00000138340.1, ENSDART00000160074.2

Conserved Domains (2) summary

cd07843
Location:437 → 728

STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1

PLN00009
Location:440 → 730

PLN00009; cyclin-dependent kinase A; Provisional

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007119.7 Reference GRCz11 Primary Assembly

Range

53948192..53960411 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009304332.3 → XP_009302607.1 cell division protein kinase 11 isoform X1

UniProtKB/TrEMBL

A0A8M3BC62

Conserved Domains (2) summary

cd07843
Location:444 → 735

STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1

PLN00009
Location:447 → 737

PLN00009; cyclin-dependent kinase A; Provisional
XM_009304335.3 → XP_009302610.1 cell division protein kinase 11 isoform X2

UniProtKB/TrEMBL

A0A8M3AVM5

Conserved Domains (2) summary

cd07843
Location:387 → 678

STKc_CDC2L1; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1

PLN00009
Location:390 → 680

PLN00009; cyclin-dependent kinase A; Provisional