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farsb phenylalanyl-tRNA synthetase subunit beta [ Danio rerio (zebrafish) ]

Gene ID: 493608, updated on 19-May-2022

Summary

Official Symbol
farsbprovided by ZNC
Official Full Name
phenylalanyl-tRNA synthetase subunit betaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-021206-2
See related
Ensembl:ENSDARG00000016864 AllianceGenome:ZFIN:ZDB-GENE-021206-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb428; farsl; zgc:92055
Summary
Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of phenylalanine-tRNA ligase complex. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; musculature system; and nervous system. Orthologous to human FARSB (phenylalanyl-tRNA synthetase subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See farsb in Genome Data Viewer
Location:
chromosome: 15
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (42264895..42283799, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (42308543..42327447, complement)
103 previous assembly Zv9 (GCF_000002035.4) 15 NC_007126.5 (40792147..40811051, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RNF152-like Neighboring gene sphingosine-1-phosphate phosphatase 2 Neighboring gene SR-related CTD-associated factor 4b Neighboring gene TIAM Rac1 associated GEF 1b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phenylalanine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in phenylalanyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within phenylalanyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of phenylalanine-tRNA ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
phenylalanine--tRNA ligase beta subunit
Names
phenylalanyl-tRNA synthetase, beta subunit
NP_001007769.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007768.1NP_001007769.1  phenylalanine--tRNA ligase beta subunit

    See identical proteins and their annotated locations for NP_001007769.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085625
    UniProtKB/TrEMBL
    Q5RKM6
    Related
    ENSDARP00000007817.5, ENSDART00000015979.6
    Conserved Domains (4) summary
    smart00873
    Location:120281
    B3_4; B3/4 domain
    PLN02265
    Location:1590
    PLN02265; probable phenylalanyl-tRNA synthetase beta chain
    cd00769
    Location:396589
    PheRS_beta_core; Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an ...
    pfam03484
    Location:314376
    B5; tRNA synthetase B5 domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    42264895..42283799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)