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arhgef39 Rho guanine nucleotide exchange factor (GEF) 39 [ Danio rerio (zebrafish) ]

Gene ID: 492469, updated on 3-Oct-2019

Summary

Official Symbol
arhgef39provided by ZNC
Official Full Name
Rho guanine nucleotide exchange factor (GEF) 39provided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-28
See related
Ensembl:ENSDARG00000013476
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
zgc:103517
Orthologs

Genomic context

See arhgef39 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (12413203..12477224, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (12414354..12478375, complement)
103 previous assembly Zv9 (GCF_000002035.4) 4 NC_007115.5 (11477727..11541758, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 173 Neighboring gene RERG/RAS-like a Neighboring gene uncharacterized LOC103910417 Neighboring gene LIM domain only 3

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
Rho guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
rho guanine nucleotide exchange factor 39

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007341.2NP_001007342.2  rho guanine nucleotide exchange factor 39 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL844512
    UniProtKB/TrEMBL
    B0R089
    Related
    ENSDARP00000012708.7, ENSDART00000027756.9
  2. NM_001328589.1NP_001315518.1  rho guanine nucleotide exchange factor 39 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 3' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.
    Source sequence(s)
    AL844512
    UniProtKB/TrEMBL
    F1QG07
    Related
    ENSDARP00000109555.1, ENSDART00000127150.3
    Conserved Domains (2) summary
    pfam00621
    Location:31200
    RhoGEF; RhoGEF domain
    cl17171
    Location:203291
    PH-like; Pleckstrin homology-like domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    12413203..12477224 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394553.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    37746..101767 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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