trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trmt10cprovided by ZNC
Official Full Name: tRNA methyltransferase 10C, mitochondrial RNase P subunitprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-12
See related: Ensembl:ENSDARG00000041575 AllianceGenome:ZFIN:ZDB-GENE-041114-12
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rg9mtd1; wu:fb53e06; zgc:103570
Summary: Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to act upstream of or within methylation and tRNA processing. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 30. Orthologous to human TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (509021..513786, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (513842..518607, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

AI497435 (e-PCR)
- UniSTS:206347

fb53e06.x1 (e-PCR)
- UniSTS:203308

fe13d01.y1 (e-PCR)
- UniSTS:196143

fb23g02.x1 (e-PCR)
- UniSTS:203080

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA (adenine(9)-N1)-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA (guanosine(9)-N1)-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial tRNA 5'-end processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of mitochondrial translation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tRNA methyltransferase 10 homolog C

Names: RNA (guanine-9-) methyltransferase domain containing 1; mitochondrial ribonuclease P protein 1

NP_001007333.2

EC 2.1.1.221

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.