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ppp1r21 protein phosphatase 1, regulatory subunit 21 [ Danio rerio (zebrafish) ]

Gene ID: 492333, updated on 27-Mar-2024

Summary

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Official Symbol
ppp1r21provided by ZNC
Official Full Name
protein phosphatase 1, regulatory subunit 21provided by ZNC
Primary source
ZFIN:ZDB-GENE-041114-8
See related
Ensembl:ENSDARG00000103144 AllianceGenome:ZFIN:ZDB-GENE-041114-8
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
klraq1; zgc:92087
Summary
Predicted to be located in endosome. Predicted to be active in early endosome. Orthologous to human PPP1R21 (protein phosphatase 1 regulatory subunit 21). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (44725..214156, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (81092..127754, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene general transcription factor IIA, 1-like Neighboring gene stonin 1 Neighboring gene polymerase (DNA directed), epsilon 2 Neighboring gene kelch domain containing 1 Neighboring gene uncharacterized LOC101883147 Neighboring gene dynein axonemal assembly factor 2 Neighboring gene RNA-binding protein FUS-like Neighboring gene uncharacterized LOC103911134 Neighboring gene uncharacterized LOC108181174 Neighboring gene uncharacterized LOC108192002 Neighboring gene reticulon 4b Neighboring gene prolyl-tRNA synthetase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Zebrafish ppp1r21 mutant as a model for the study of primary biliary cholangitis.
    Title: Zebrafish ppp1r21 mutant as a model for the study of primary biliary cholangitis.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in early endosome ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 21
Names
KLRAQ motif-containing protein 1
coiled-coil domain-containing protein 128

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007299.1 → NP_001007300.1  protein phosphatase 1 regulatory subunit 21

    See identical proteins and their annotated locations for NP_001007300.1

    Status: PROVISIONAL

    Source sequence(s)
    BC085632
    UniProtKB/Swiss-Prot
    Q5U3A8
    Related
    ENSDARP00000135569.2, ENSDART00000169273.2
    Conserved Domains (2) summary
    pfam10205
    Location:9 → 109
    KLRAQ; Predicted coiled-coil domain-containing protein
    pfam10212
    Location:253 → 656
    TTKRSYEDQ; Predicted coiled-coil domain-containing protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    44725..214156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5U3A8.1 GenPept UniProtKB/Swiss-Prot:Q5U3A8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.