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GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 [ Canis lupus familiaris (dog) ]

Gene ID: 492223, updated on 25-Jul-2026
Official Symbol
GABRA3provided by VGNC
Official Full Name
gamma-aminobutyric acid type A receptor subunit alpha3provided by VGNC
Primary source
VGNC:VGNC:41055
See related
RGD:12062085
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See GABRA3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (122414804..122682830, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (105530627..105839355, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (121458330..121767417, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (119092886..119401752, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (121583594..121892563, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L19-like Neighboring gene melanoma-associated antigen 10-like Neighboring gene melanoma-associated antigen 8-like Neighboring gene U6 spliceosomal RNA Neighboring gene microRNA mir-105a Neighboring gene microRNA mir-105b Neighboring gene 40S ribosomal protein S6-like Neighboring gene chromobox protein homolog 3-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GABA-A receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GABA-gated chloride ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables benzodiazepine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inhibitory extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gamma-aminobutyric acid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, GABAergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GABA-A receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
gamma-aminobutyric acid receptor subunit alpha-3
Names
gamma-aminobutyric acid type A receptor alpha3 subunit

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    122414804..122682830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038451166.1 → XP_038307094.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X1

    Conserved Domains (2) summary
    cd03558
    Location:191 → 205
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:75 → 259
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

  2. XM_038451165.1 → XP_038307093.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X1

    Conserved Domains (2) summary
    cd03558
    Location:191 → 205
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:75 → 259
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    119092886..119401752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524618.1 → XP_038380546.1  

    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

  2. XM_038524617.1 → XP_038380545.1  

    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    121583594..121892563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653091.1 → XP_038509019.1  

    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

  2. XM_038653090.1 → XP_038509018.1  

    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    121458330..121767417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038588582.1 → XP_038444510.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LHF9
    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

  2. XM_038588581.1 → XP_038444509.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LHF9
    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    105530627..105839355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_549343.6 → XP_549343.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X5

    See identical proteins and their annotated locations for XP_549343.1

    UniProtKB/TrEMBL
    A0A8C0LHF9
    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)

  2. XM_005641961.4 → XP_005642018.1  gamma-aminobutyric acid receptor subunit alpha-3 isoform X5

    See identical proteins and their annotated locations for XP_005642018.1

    UniProtKB/TrEMBL
    A0A8C0LHF9
    Conserved Domains (2) summary
    TIGR00860
    Location:69 → 478
    LIC; Cation transporter family protein
    cd19036
    Location:75 → 274
    LGIC_ECD_GABAAR_A3; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-3 (GABAAR-A3 or GABRA3)
Nucleotide Protein
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