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XPNPEP2 X-prolyl aminopeptidase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 492124, updated on 25-Jul-2026
Official Symbol
XPNPEP2provided by VGNC
Official Full Name
X-prolyl aminopeptidase 2provided by VGNC
Primary source
VGNC:VGNC:48458
See related
Ensembl:ENSCAFG00845031010 RGD:12141959
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See XPNPEP2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (102803123..102831127)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (87125596..87153589)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (101845408..101873412)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (100221644..100249427)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (102067636..102095611)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene OCRL inositol polyphosphate-5-phosphatase Neighboring gene apelin Neighboring gene SAM and SH3 domain containing 3 Neighboring gene zinc finger DHHC-type palmitoyltransferase 9 Neighboring gene 60S ribosomal protein L7a-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloaminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
xaa-Pro aminopeptidase 2
XP_038306760.1
XP_038320843.1
XP_038380229.1
XP_038444196.1
XP_038508717.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    102803123..102831127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450832.1 → XP_038306760.1  xaa-Pro aminopeptidase 2

    UniProtKB/TrEMBL
    A0A8C0JMR2, A0A8I3Q8E3
    Related
    ENSCAFP00845043350.1, ENSCAFT00845055126.1
    Conserved Domains (4) summary
    cd01085
    Location:366 → 584
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:55 → 191
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:586 → 649
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:196 → 362
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    100221644..100249427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524301.1 → XP_038380229.1  

    Conserved Domains (4) summary
    cd01085
    Location:366 → 584
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:55 → 191
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:586 → 649
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:196 → 362
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    102067636..102095611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652789.1 → XP_038508717.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    101845408..101873412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038588268.1 → XP_038444196.1  xaa-Pro aminopeptidase 2

    UniProtKB/TrEMBL
    A0A8C0JMR2, A0A8I3Q8E3
    Conserved Domains (4) summary
    cd01085
    Location:366 → 584
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:55 → 191
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:586 → 649
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:196 → 362
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    87125596..87153589
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038464915.1 → XP_038320843.1  xaa-Pro aminopeptidase 2

    UniProtKB/TrEMBL
    A0A8C0JMR2, A0A8I3Q8E3
    Conserved Domains (4) summary
    cd01085
    Location:366 → 584
    APP; X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, ...
    pfam01321
    Location:55 → 191
    Creatinase_N; Creatinase/Prolidase N-terminal domain
    pfam16188
    Location:586 → 649
    Peptidase_M24_C; C-terminal region of peptidase_M24
    pfam16189
    Location:196 → 362
    Creatinase_N_2; Creatinase/Prolidase N-terminal domain
Nucleotide Protein
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