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TBC1D8B TBC1 domain family member 8B [ Canis lupus familiaris (dog) ]

Gene ID: 492052, updated on 27-Jun-2026
Official Symbol
TBC1D8Bprovided by VGNC
Official Full Name
TBC1 domain family member 8Bprovided by VGNC
Primary source
VGNC:VGNC:47152
See related
Ensembl:ENSCAFG00845016942 RGD:12431627
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See TBC1D8B in Genome Data Viewer
Location:
chromosome: X
Exon count:
21
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (82004359..82073050)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (66480066..66548750)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (80957954..81026641)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (79469282..79537966)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (81178420..81247654)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene RPA1 related single stranded DNA binding protein, X-linked Neighboring gene uncharacterized LOC111094760 Neighboring gene ring finger protein 128 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene ripply transcriptional repressor 1 Neighboring gene claudin 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
TBC1 domain family member 8B

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    82004359..82073050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450564.1 → XP_038306492.1  TBC1 domain family member 8B isoform X2

    UniProtKB/TrEMBL
    A0A8I3S2E4
    Conserved Domains (3) summary
    smart00164
    Location:451 → 659
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

  2. XM_038450563.1 → XP_038306491.1  TBC1 domain family member 8B isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZ96, A0A8I3S2D8, A0A8I3S2E4
    Related
    ENSCAFP00845023548.1, ENSCAFT00845030014.1
    Conserved Domains (3) summary
    smart00164
    Location:486 → 694
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    79469282..79537966
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524016.1 → XP_038379944.1  

    Conserved Domains (3) summary
    smart00164
    Location:451 → 659
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

  2. XM_038524015.1 → XP_038379943.1  

    Conserved Domains (3) summary
    smart00164
    Location:486 → 694
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    81178420..81247654
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652512.1 → XP_038508440.1  

    Conserved Domains (3) summary
    smart00164
    Location:451 → 659
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

  2. XM_038652511.1 → XP_038508439.1  

    Conserved Domains (3) summary
    smart00164
    Location:486 → 694
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    80957954..81026641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038587995.1 → XP_038443923.1  TBC1 domain family member 8B isoform X2

    UniProtKB/TrEMBL
    A0A8I3S2E4
    Conserved Domains (3) summary
    smart00164
    Location:451 → 659
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

  2. XM_038587994.1 → XP_038443922.1  TBC1 domain family member 8B isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZ96, A0A8I3S2D8, A0A8I3S2E4
    Conserved Domains (3) summary
    smart00164
    Location:486 → 694
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    66480066..66548750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005641635.4 → XP_005641692.1  TBC1 domain family member 8B isoform X2

    UniProtKB/TrEMBL
    A0A8I3S2E4
    Conserved Domains (3) summary
    smart00164
    Location:451 → 659
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

  2. XM_549172.7 → XP_549172.3  TBC1 domain family member 8B isoform X1

    UniProtKB/TrEMBL
    A0A8C0JZ96, A0A8I3S2D8, A0A8I3S2E4
    Conserved Domains (3) summary
    smart00164
    Location:486 → 694
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13352
    Location:296 → 388
    PH-GRAM2_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13350
    Location:156 → 254
    PH-GRAM1_TBC1D8B; TBC1 domain family member 8B (TBC1D8B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1
Nucleotide Protein
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