LHX2 LIM homeobox 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: LHX2provided by VGNC
Official Full Name: LIM homeobox 2provided by VGNC
Primary source: VGNC:VGNC:42663
See related: Ensembl:ENSCAFG00845010906
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	9	NC_051813.1 (59745814..59766310, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	9	NC_006591.4 (58022250..58042687, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	9	NC_049230.1 (58910400..58930871, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	9	NC_049269.1 (58502870..58523325, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	9	NC_049750.1 (58819702..58840014, complement)

Chromosome 9 - NC_051813.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in neuron differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LIM/homeobox protein Lhx2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051813.1 Reference ROS_Cfam_1.0

Range

59745814..59766310 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038678662.1 → XP_038534590.1 LIM/homeobox protein Lhx2

UniProtKB/TrEMBL

A0A8C0PPM4, A0A8C0R1W8, A0A8I3RW43

Related

ENSCAFP00845015041.1, ENSCAFT00845019250.1

Conserved Domains (4) summary

cd09377
Location:111 → 169

LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family

cd09469
Location:43 → 106

LIM1_Lhx2; The first LIM domain of Lhx2

COG5576
Location:247 → 368

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:270 → 323

Homeobox; Homeobox domain

Alternate UMICH_Zoey_3.1

Genomic

NC_049269.1 Alternate UMICH_Zoey_3.1

Range

58502870..58523325 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038487494.1 → XP_038343422.1 LIM/homeobox protein Lhx2

Conserved Domains (4) summary

cd09377
Location:111 → 169

LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family

cd09469
Location:43 → 106

LIM1_Lhx2; The first LIM domain of Lhx2

COG5576
Location:247 → 368

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:270 → 323

Homeobox; Homeobox domain

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049750.1 Alternate UNSW_CanFamBas_1.0

Range

58819702..58840014 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038613355.1 → XP_038469283.1 LIM/homeobox protein Lhx2

Conserved Domains (4) summary

cd09377
Location:111 → 169

LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family

cd09469
Location:43 → 106

LIM1_Lhx2; The first LIM domain of Lhx2

COG5576
Location:247 → 368

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:270 → 323

Homeobox; Homeobox domain

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049230.1 Alternate UU_Cfam_GSD_1.0

Range

58910400..58930871 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038549423.1 → XP_038405351.1 LIM/homeobox protein Lhx2

UniProtKB/TrEMBL

A0A8C0PPM4, A0A8C0R1W8, A0A8I3RW43

Conserved Domains (4) summary

cd09377
Location:111 → 169

LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family

cd09469
Location:43 → 106

LIM1_Lhx2; The first LIM domain of Lhx2

COG5576
Location:247 → 368

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:270 → 323

Homeobox; Homeobox domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

58022250..58042687 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_858575.5 → XP_863668.2 LIM/homeobox protein Lhx2

See identical proteins and their annotated locations for XP_863668.2

UniProtKB/TrEMBL

A0A8C0PPM4, A0A8C0R1W8, A0A8I3RW43

Conserved Domains (4) summary

cd09377
Location:111 → 169

LIM2_Lhx2_Lhx9; The second LIM domain of Lhx2 and Lhx9 family

cd09469
Location:43 → 106

LIM1_Lhx2; The first LIM domain of Lhx2

COG5576
Location:247 → 368

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:270 → 323

Homeobox; Homeobox domain