U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SLC25A25 solute carrier family 25 member 25 [ Canis lupus familiaris (dog) ]

Gene ID: 491321, updated on 25-Jul-2026
Official Symbol
SLC25A25provided by VGNC
Official Full Name
solute carrier family 25 member 25provided by VGNC
Primary source
VGNC:VGNC:46301
See related
RGD:12243224
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See SLC25A25 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (56285169..56316835, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (54553071..54588912, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (55446944..55482811, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (55040512..55076587, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (55355242..55391319, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L30-like Neighboring gene lipocalin 2 Neighboring gene prostaglandin E synthase 2 Neighboring gene uncharacterized LOC119873364 Neighboring gene nuclear apoptosis inducing factor 1 Neighboring gene uncharacterized LOC119873366 Neighboring gene uncharacterized LOC119873365

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
calcium-binding mitochondrial carrier protein SCaMC-2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    56285169..56316835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675151.1 → XP_038531079.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1

    Conserved Domains (2) summary
    pfam00153
    Location:438 → 494
    Mito_carr; Mitochondrial carrier protein
    pfam13499
    Location:52 → 110
    EF-hand_7; EF-hand domain pair

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    55040512..55076587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038487296.1 → XP_038343224.1  

  2. XM_038487295.1 → XP_038343223.1  

  3. XM_038487305.1 → XP_038343233.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  4. XM_038487303.1 → XP_038343231.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  5. XM_038487297.1 → XP_038343225.1  

    Conserved Domains (5) summary
    PTZ00169
    Location:223 → 477
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:102 → 131
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:73 → 97
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:102 → 191
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:73 → 145
    EFh_PEF; The penta-EF hand (PEF) family

  6. XM_038487298.1 → XP_038343226.1  

    Conserved Domains (3) summary
    PTZ00169
    Location:211 → 465
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15897
    Location:73 → 97
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:73 → 159
    EFh_PEF; The penta-EF hand (PEF) family

  7. XM_038487306.1 → XP_038343234.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  8. XM_038487301.1 → XP_038343229.1  

  9. XM_038487299.1 → XP_038343227.1  

  10. XM_038487302.1 → XP_038343230.1  

    Conserved Domains (5) summary
    PTZ00169
    Location:173 → 427
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:52 → 81
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:21 → 47
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:52 → 141
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:21 → 95
    EFh_PEF; The penta-EF hand (PEF) family

  11. XM_038487304.1 → XP_038343232.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    55355242..55391319 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038613168.1 → XP_038469096.1  

  2. XM_038613167.1 → XP_038469095.1  

  3. XM_038613177.1 → XP_038469105.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  4. XM_038613174.1 → XP_038469102.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  5. XM_038613169.1 → XP_038469097.1  

    Conserved Domains (5) summary
    PTZ00169
    Location:223 → 477
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:102 → 131
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:73 → 97
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:102 → 191
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:73 → 145
    EFh_PEF; The penta-EF hand (PEF) family

  6. XM_038613170.1 → XP_038469098.1  

    Conserved Domains (3) summary
    PTZ00169
    Location:211 → 465
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15897
    Location:73 → 97
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:73 → 159
    EFh_PEF; The penta-EF hand (PEF) family

  7. XM_038613178.1 → XP_038469106.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  8. XM_038613172.1 → XP_038469100.1  

  9. XM_038613171.1 → XP_038469099.1  

  10. XM_038613173.1 → XP_038469101.1  

    Conserved Domains (5) summary
    PTZ00169
    Location:173 → 427
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:52 → 81
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:21 → 47
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:52 → 141
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:21 → 95
    EFh_PEF; The penta-EF hand (PEF) family

  11. XM_038613175.1 → XP_038469103.1  

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    55446944..55482811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038549223.1 → XP_038405151.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X19

    UniProtKB/TrEMBL
    A0A8C0KR98

  2. XM_038549222.1 → XP_038405150.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X18

  3. XM_038549232.1 → XP_038405160.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X25

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  4. XM_038549229.1 → XP_038405157.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X25

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  5. XM_038549224.1 → XP_038405152.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X20

  6. XM_038549225.1 → XP_038405153.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X21

    UniProtKB/TrEMBL
    A0A8C0R281

  7. XM_038549233.1 → XP_038405161.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X25

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  8. XM_038549227.1 → XP_038405155.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X23

    UniProtKB/TrEMBL
    A0A8C0R1X1

  9. XM_038549226.1 → XP_038405154.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X22

  10. XM_038549228.1 → XP_038405156.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X24

    Conserved Domains (5) summary
    PTZ00169
    Location:173 → 427
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:52 → 81
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:21 → 47
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:52 → 141
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:21 → 95
    EFh_PEF; The penta-EF hand (PEF) family

  11. XM_038549231.1 → XP_038405159.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X25

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    54553071..54588912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_857280.6 → XP_862373.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X27

    UniProtKB/TrEMBL
    A0A8C0KR98
    Conserved Domains (3) summary
    cd15897
    Location:46 → 77
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:53 → 172
    EFh_PEF; The penta-EF hand (PEF) family
    cl28162
    Location:224 → 478
    Mito_carr; Mitochondrial carrier protein

  2. XM_005625310.4 → XP_005625367.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X26

    Conserved Domains (5) summary
    cd15898
    Location:115 → 144
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:46 → 77
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:46 → 158
    EFh_PEF; The penta-EF hand (PEF) family
    cl28162
    Location:236 → 490
    Mito_carr; Mitochondrial carrier protein
    cl28895
    Location:115 → 204
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

  3. XM_022423774.2 → XP_022279482.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X33

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  4. XM_022423772.2 → XP_022279480.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X33

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  5. XM_548442.7 → XP_548442.3  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X28

    Conserved Domains (5) summary
    PTZ00169
    Location:223 → 477
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:102 → 131
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:73 → 97
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:102 → 191
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:73 → 145
    EFh_PEF; The penta-EF hand (PEF) family

  6. XM_857389.6 → XP_862482.2  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X29

    Conserved Domains (3) summary
    PTZ00169
    Location:211 → 465
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15897
    Location:73 → 97
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:73 → 159
    EFh_PEF; The penta-EF hand (PEF) family

  7. XM_022423773.2 → XP_022279481.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X33

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

  8. XM_857417.6 → XP_862510.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X31

    UniProtKB/TrEMBL
    A0A8C0R1X1
    Conserved Domains (3) summary
    cd15897
    Location:53 → 77
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:53 → 139
    EFh_PEF; The penta-EF hand (PEF) family
    cl28162
    Location:191 → 445
    Mito_carr; Mitochondrial carrier protein

  9. XM_005625311.4 → XP_005625368.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X30

    Conserved Domains (5) summary
    cd15898
    Location:82 → 111
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:53 → 77
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:53 → 125
    EFh_PEF; The penta-EF hand (PEF) family
    cl28162
    Location:203 → 457
    Mito_carr; Mitochondrial carrier protein
    cl28895
    Location:82 → 171
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

  10. XM_014117031.3 → XP_013972506.2  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X32

    Conserved Domains (5) summary
    PTZ00169
    Location:173 → 427
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    cd15898
    Location:52 → 81
    EFh_PI-PLC; EF-hand motif [structural motif]
    cd15897
    Location:21 → 47
    EFh_PEF; EF-hand motif [structural motif]
    cl28895
    Location:52 → 141
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl25352
    Location:21 → 95
    EFh_PEF; The penta-EF hand (PEF) family

  11. XM_038618450.1 → XP_038474378.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X33

    Conserved Domains (1) summary
    PTZ00169
    Location:100 → 354
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials