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ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Canis lupus familiaris (dog) ]

Gene ID: 491292, updated on 30-May-2018

Summary

Official Symbol
ABL1provided by VGNC
Official Full Name
ABL proto-oncogene 1, non-receptor tyrosine kinaseprovided by VGNC
Primary source
VGNC:VGNC:54912
See related
Ensembl:ENSCAFG00000019938
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs

Genomic context

See ABL1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 9 NC_006591.3 (53118462..53262092, complement)

Chromosome 9 - NC_006591.3Genomic Context describing neighboring genes Neighboring gene fibrinogen C domain containing 1 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene serine/arginine repetitive matrix protein 3-like Neighboring gene exosome component 2 Neighboring gene far upstream element binding protein 3

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006591.3 Chromosome 9 Reference CanFam3.1 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

General protein information

Preferred Names
tyrosine-protein kinase ABL1
Names
c-abl oncogene 1, non-receptor tyrosine kinase
c-abl oncogene 1, receptor tyrosine kinase
v-abl Abelson murine leukemia viral oncogene homolog 1
XP_005625289.1
XP_548413.3

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006591.3 Reference CanFam3.1 Primary Assembly

    Range
    53118462..53262092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_548413.6XP_548413.3  tyrosine-protein kinase ABL1 isoform X1

    UniProtKB/TrEMBL
    F1PEX6
    Related
    ENSCAFP00000029535.3, ENSCAFT00000031723.3
    Conserved Domains (5) summary
    smart00808
    Location:10261150
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:142235
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:84137
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:254516
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:261512
    Pkinase_Tyr; Protein tyrosine kinase
  2. XM_005625232.2XP_005625289.1  tyrosine-protein kinase ABL1 isoform X2

    UniProtKB/TrEMBL
    F1PEX7
    Related
    ENSCAFP00000029534.3, ENSCAFT00000031722.4
    Conserved Domains (5) summary
    smart00808
    Location:10071131
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:123216
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:65118
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:235497
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:242493
    Pkinase_Tyr; Protein tyrosine kinase
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