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SARM1 sterile alpha and TIR motif containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 491165, updated on 17-Aug-2024

Summary

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Official Symbol
SARM1provided by VGNC
Official Full Name
sterile alpha and TIR motif containing 1provided by VGNC
Primary source
VGNC:VGNC:45868
See related
Ensembl:ENSCAFG00845007295
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See SARM1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (43441401..43465669)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (41779152..41803421)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (42593916..42618176)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (42225631..42247631)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (42516850..42540910)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 199 Neighboring gene SEBOX homeobox Neighboring gene vitronectin Neighboring gene solute carrier family 46 member 1 Neighboring gene solute carrier family 13 member 2 Neighboring gene uncharacterized LOC119873325 Neighboring gene forkhead box N1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ nucleosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of MyD88-independent toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to axon injury IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterile alpha and TIR motif-containing protein 1; NAD(+) hydrolase SARM1
XP_038342321.1
XP_038404159.1
XP_038468125.1
XP_038533382.1
XP_548285.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    43441401..43465669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038677454.1 → XP_038533382.1  NAD(+) hydrolase SARM1

    UniProtKB/TrEMBL
    A0A8C0KHC9, A0A8C0NAQ7, A0A8I3N082
    Related
    ENSCAFP00845010057.1, ENSCAFT00845012904.1
    Conserved Domains (3) summary
    cd09502
    Location:479 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    smart00255
    Location:562 → 702
    TIR; Toll - interleukin 1 - resistance
    cl15755
    Location:409 → 477
    SAM_superfamily; SAM (Sterile alpha motif )

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    42225631..42247631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038486393.1 → XP_038342321.1  NAD(+) hydrolase SARM1

    Conserved Domains (3) summary
    cd09502
    Location:479 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    smart00255
    Location:562 → 702
    TIR; Toll - interleukin 1 - resistance
    cl15755
    Location:409 → 477
    SAM_superfamily; SAM (Sterile alpha motif )

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    42516850..42540910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038612197.1 → XP_038468125.1  NAD(+) hydrolase SARM1

    Conserved Domains (3) summary
    cd09502
    Location:479 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    smart00255
    Location:562 → 702
    TIR; Toll - interleukin 1 - resistance
    cl15755
    Location:409 → 477
    SAM_superfamily; SAM (Sterile alpha motif )

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    42593916..42618176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038548231.1 → XP_038404159.1  NAD(+) hydrolase SARM1

    UniProtKB/TrEMBL
    A0A8C0KHC9, A0A8C0NAQ7, A0A8I3N082
    Conserved Domains (3) summary
    cd09502
    Location:479 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    smart00255
    Location:562 → 702
    TIR; Toll - interleukin 1 - resistance
    cl15755
    Location:409 → 477
    SAM_superfamily; SAM (Sterile alpha motif )

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41779152..41803421
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_548285.7 → XP_548285.3  NAD(+) hydrolase SARM1

    UniProtKB/TrEMBL
    A0A8C0KHC9, A0A8C0NAQ7, A0A8I3N082
    Conserved Domains (3) summary
    cd09502
    Location:479 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    smart00255
    Location:562 → 702
    TIR; Toll - interleukin 1 - resistance
    cl15755
    Location:409 → 477
    SAM_superfamily; SAM (Sterile alpha motif )
Nucleotide Protein
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