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TRIM25 tripartite motif containing 25 [ Canis lupus familiaris (dog) ]

Gene ID: 491103, updated on 25-Jul-2026
Official Symbol
TRIM25provided by VGNC
Official Full Name
tripartite motif containing 25provided by VGNC
Primary source
VGNC:VGNC:47810
See related
Ensembl:ENSCAFG00845018182 RGD:12361388
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See TRIM25 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (32511355..32533408, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (30943465..30965495, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (31664093..31686131, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (31296490..31318526, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (31580728..31602758, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene chromosome 9 C17orf67 homolog Neighboring gene diacylglycerol kinase epsilon Neighboring gene coilin Neighboring gene serine carboxypeptidase 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 ubiquitin/ISG15 ligase TRIM25
XP_038341954.1
XP_038403735.1
XP_038467717.1
XP_038532941.1
XP_548223.3

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    32511355..32533408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038677013.1 → XP_038532941.1  E3 ubiquitin/ISG15 ligase TRIM25

    UniProtKB/TrEMBL
    A0A8I3S0A8
    Related
    ENSCAFP00845025140.1, ENSCAFT00845032161.1
    Conserved Domains (7) summary
    COG0419
    Location:188 → 367
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    TIGR00599
    Location:1 → 99
    rad18; DNA repair protein rad18
    cd13736
    Location:462 → 628
    SPRY_PRY_TRIM25; PRY/SPRY domain in tripartite motif-containing domain 25 (TRIM25)
    cd00162
    Location:13 → 53
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cd19776
    Location:150 → 186
    Bbox2_TRIM25_C-IV; B-box-type 2 zinc finger found in tripartite motif-containing protein 25 (TRIM25) and similar proteins
    cd19842
    Location:101 → 147
    Bbox1_TRIM25-like_C-IV; B-box-type 1 zinc finger found in tripartite motif-containing proteins, TRIM25, TRIM47 and similar proteins
    cl17238
    Location:11 → 54
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    31296490..31318526 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038486026.1 → XP_038341954.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    31580728..31602758 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038611789.1 → XP_038467717.1  

    Conserved Domains (7) summary
    COG0419
    Location:188 → 367
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    TIGR00599
    Location:1 → 99
    rad18; DNA repair protein rad18
    cd13736
    Location:462 → 628
    SPRY_PRY_TRIM25; PRY/SPRY domain in tripartite motif-containing domain 25 (TRIM25)
    cd00162
    Location:13 → 53
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cd19776
    Location:150 → 186
    Bbox2_TRIM25_C-IV; B-box-type 2 zinc finger found in tripartite motif-containing protein 25 (TRIM25) and similar proteins
    cd19842
    Location:101 → 147
    Bbox1_TRIM25-like_C-IV; B-box-type 1 zinc finger found in tripartite motif-containing proteins, TRIM25, TRIM47 and similar proteins
    cl17238
    Location:11 → 54
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    31664093..31686131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547807.1 → XP_038403735.1  E3 ubiquitin/ISG15 ligase TRIM25

    UniProtKB/TrEMBL
    A0A8I3S0A8
    Conserved Domains (7) summary
    COG0419
    Location:188 → 367
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    TIGR00599
    Location:1 → 99
    rad18; DNA repair protein rad18
    cd13736
    Location:462 → 628
    SPRY_PRY_TRIM25; PRY/SPRY domain in tripartite motif-containing domain 25 (TRIM25)
    cd00162
    Location:13 → 53
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cd19776
    Location:150 → 186
    Bbox2_TRIM25_C-IV; B-box-type 2 zinc finger found in tripartite motif-containing protein 25 (TRIM25) and similar proteins
    cd19842
    Location:101 → 147
    Bbox1_TRIM25-like_C-IV; B-box-type 1 zinc finger found in tripartite motif-containing proteins, TRIM25, TRIM47 and similar proteins
    cl17238
    Location:11 → 54
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30943465..30965495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_548223.7 → XP_548223.3  E3 ubiquitin/ISG15 ligase TRIM25

    UniProtKB/TrEMBL
    A0A8I3S0A8
    Conserved Domains (7) summary
    COG0419
    Location:188 → 367
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    TIGR00599
    Location:1 → 99
    rad18; DNA repair protein rad18
    cd13736
    Location:462 → 628
    SPRY_PRY_TRIM25; PRY/SPRY domain in tripartite motif-containing domain 25 (TRIM25)
    cd00162
    Location:13 → 53
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cd19776
    Location:150 → 186
    Bbox2_TRIM25_C-IV; B-box-type 2 zinc finger found in tripartite motif-containing protein 25 (TRIM25) and similar proteins
    cd19842
    Location:101 → 147
    Bbox1_TRIM25-like_C-IV; B-box-type 1 zinc finger found in tripartite motif-containing proteins, TRIM25, TRIM47 and similar proteins
    cl17238
    Location:11 → 54
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
Nucleotide Protein
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