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NAGLU N-acetyl-alpha-glucosaminidase [ Canis lupus familiaris (dog) ]

Gene ID: 490965, updated on 25-Jul-2026
Official Symbol
NAGLUprovided by VGNC
Official Full Name
N-acetyl-alpha-glucosaminidaseprovided by VGNC
Primary source
VGNC:VGNC:43609
See related
Ensembl:ENSCAFG00845008828 RGD:12238350
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See NAGLU in Genome Data Viewer
Location:
chromosome: 9
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (21126245..21133008, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (19869143..19875907, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (20281366..20288130, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (19912074..19918837, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (20177305..20184070, complement)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene Coenzyme A synthase Neighboring gene hydroxysteroid 17-beta dehydrogenase 1 Neighboring gene ATPase H+ transporting V0 subunit a1 Neighboring gene caveolae associated protein 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. An exonic insertion in the NAGLU gene causing Mucopolysaccharidosis IIIB in Schipperke dogs. Raj K, et al. Sci Rep, 2020 Feb 21. PMID 32081995, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An exonic insertion in the NAGLU gene causing Mucopolysaccharidosis IIIB in Schipperke dogs.
    Title: An exonic insertion in the NAGLU gene causing Mucopolysaccharidosis IIIB in Schipperke dogs.
Submit: New GeneRIF Correction

Homology

Preferred Names
alpha-N-acetylglucosaminidase
Names
N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB)
XP_038341437.1
XP_038403201.1
XP_038467171.1
XP_038532358.1
XP_548088.2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    21126245..21133008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038676430.1 → XP_038532358.1  alpha-N-acetylglucosaminidase

    UniProtKB/TrEMBL
    A0A8C0KKN2, A0A8I3NA03
    Related
    ENSCAFP00845012054.1, ENSCAFT00845015519.1
    Conserved Domains (3) summary
    pfam05089
    Location:131 → 466
    NAGLU; Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
    pfam12971
    Location:35 → 116
    NAGLU_N; Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
    pfam12972
    Location:475 → 729
    NAGLU_C; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    19912074..19918837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038485509.1 → XP_038341437.1  

    Conserved Domains (3) summary
    pfam05089
    Location:131 → 466
    NAGLU; Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
    pfam12971
    Location:35 → 116
    NAGLU_N; Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
    pfam12972
    Location:475 → 729
    NAGLU_C; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    20177305..20184070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038611243.1 → XP_038467171.1  

    Conserved Domains (3) summary
    pfam05089
    Location:131 → 466
    NAGLU; Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
    pfam12971
    Location:35 → 116
    NAGLU_N; Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
    pfam12972
    Location:475 → 729
    NAGLU_C; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    20281366..20288130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038547273.1 → XP_038403201.1  alpha-N-acetylglucosaminidase

    UniProtKB/TrEMBL
    A0A8C0KKN2, A0A8I3NA03
    Conserved Domains (3) summary
    pfam05089
    Location:131 → 466
    NAGLU; Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
    pfam12971
    Location:35 → 116
    NAGLU_N; Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
    pfam12972
    Location:475 → 729
    NAGLU_C; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    19869143..19875907 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_548088.7 → XP_548088.2  alpha-N-acetylglucosaminidase

    UniProtKB/TrEMBL
    A0A8C0KKN2, A0A8I3NA03
    Conserved Domains (3) summary
    pfam05089
    Location:131 → 466
    NAGLU; Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
    pfam12971
    Location:35 → 116
    NAGLU_N; Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
    pfam12972
    Location:475 → 729
    NAGLU_C; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
Nucleotide Protein
Heading Accession and Version

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