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MOK MOK protein kinase [ Canis lupus familiaris (dog) ]

Gene ID: 490863, updated on 25-Jul-2026
Official Symbol
MOKprovided by VGNC
Official Full Name
MOK protein kinaseprovided by VGNC
Primary source
VGNC:VGNC:43312
See related
Ensembl:ENSCAFG00845005653 RGD:12306799
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
RAGE
Orthologs
all
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Try the new Transcripts and proteins table
See MOK in Genome Data Viewer
Location:
chromosome: 8
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (70486598..70547831, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (69722999..69784172, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (70619733..70678221, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (70154016..70212532, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (70219021..70277520, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene heat shock protein 90 alpha family class A member 1 Neighboring gene uncharacterized LOC106559137 Neighboring gene WD repeat domain 20 Neighboring gene uncharacterized LOC119872932 Neighboring gene transfer RNA isoleucine (anticodon AAU)

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
MAPK/MAK/MRK overlapping kinase
Names
renal tumor antigen
XP_005623882.1
XP_005623883.1
XP_022278095.1
XP_022278096.1
XP_038340190.1
XP_038340191.1
XP_038340192.1
XP_038340193.1
XP_038340194.1
XP_038340195.1
XP_038401707.1
XP_038401708.1
XP_038401709.1
XP_038401710.1
XP_038401711.1
XP_038401712.1
XP_038452236.1
XP_038452239.1
XP_038465786.1
XP_038465787.1
XP_038465788.1
XP_038465789.1
XP_038465790.1
XP_038465791.1
XP_038530618.1
XP_038530619.1
XP_038530620.1
XP_038530621.1
XP_038530622.1
XP_038530623.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    70486598..70547831 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674690.1 → XP_038530618.1  MAPK/MAK/MRK overlapping kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3RST8
    Related
    ENSCAFP00845007863.1, ENSCAFT00845010081.1
    Conserved Domains (1) summary
    cd07831
    Location:26 → 307
    STKc_MOK; Catalytic domain of the Serine/Threonine Kinase, MAPK/MAK/MRK Overlapping Kinase

  2. XM_038674691.1 → XP_038530619.1  MAPK/MAK/MRK overlapping kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3MWG6, A0A8I3RST8
    Related
    ENSCAFP00845007839.1, ENSCAFT00845010046.1
    Conserved Domains (1) summary
    cd07831
    Location:4 → 285
    STKc_MOK; Catalytic domain of the Serine/Threonine Kinase, MAPK/MAK/MRK Overlapping Kinase

  3. XM_038674693.1 → XP_038530621.1  MAPK/MAK/MRK overlapping kinase isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 177
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038674692.1 → XP_038530620.1  MAPK/MAK/MRK overlapping kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3RST8
    Conserved Domains (1) summary
    cl21453
    Location:6 → 195
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038674694.1 → XP_038530622.1  MAPK/MAK/MRK overlapping kinase isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 177
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038674695.1 → XP_038530623.1  MAPK/MAK/MRK overlapping kinase isoform X5

    Conserved Domains (1) summary
    cl21453
    Location:1 → 149
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_005431526.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    70154016..70212532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484262.1 → XP_038340190.1  

  2. XM_038484263.1 → XP_038340191.1  

  3. XM_038484265.1 → XP_038340193.1  

  4. XM_038484264.1 → XP_038340192.1  

  5. XM_038484266.1 → XP_038340194.1  

  6. XM_038484267.1 → XP_038340195.1  

RNA

  1. XR_005329990.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    70219021..70277520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609858.1 → XP_038465786.1  

  2. XM_038609859.1 → XP_038465787.1  

    Conserved Domains (1) summary
    cd07831
    Location:4 → 285
    STKc_MOK; Catalytic domain of the Serine/Threonine Kinase, MAPK/MAK/MRK Overlapping Kinase

  3. XM_038609861.1 → XP_038465789.1  

    Conserved Domains (1) summary
    cl21453
    Location:1 → 177
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038609860.1 → XP_038465788.1  

    Conserved Domains (1) summary
    cl21453
    Location:6 → 195
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038609862.1 → XP_038465790.1  

    Conserved Domains (1) summary
    cl21453
    Location:1 → 177
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038609863.1 → XP_038465791.1  

    Conserved Domains (1) summary
    cl21453
    Location:1 → 149
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_005398259.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    70619733..70678221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545779.1 → XP_038401707.1  MAPK/MAK/MRK overlapping kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3RST8

  2. XM_038545780.1 → XP_038401708.1  MAPK/MAK/MRK overlapping kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3RST8

  3. XM_038545782.1 → XP_038401710.1  MAPK/MAK/MRK overlapping kinase isoform X4

  4. XM_038545781.1 → XP_038401709.1  MAPK/MAK/MRK overlapping kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3RST8

  5. XM_038545783.1 → XP_038401711.1  MAPK/MAK/MRK overlapping kinase isoform X4

  6. XM_038545784.1 → XP_038401712.1  MAPK/MAK/MRK overlapping kinase isoform X5

RNA

  1. XR_005363805.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    69722999..69784172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005623825.4 → XP_005623882.1  MAPK/MAK/MRK overlapping kinase isoform X1

    UniProtKB/TrEMBL
    A0A8I3RST8
    Conserved Domains (2) summary
    smart00220
    Location:26 → 307
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07831
    Location:26 → 307
    STKc_MOK; Catalytic domain of the Serine/Threonine Kinase, MAPK/MAK/MRK Overlapping Kinase

  2. XM_005623826.4 → XP_005623883.1  MAPK/MAK/MRK overlapping kinase isoform X2

    UniProtKB/TrEMBL
    A0A8I3MWG6, A0A8I3RST8
    Conserved Domains (1) summary
    cd07831
    Location:4 → 285
    STKc_MOK; Catalytic domain of the Serine/Threonine Kinase, MAPK/MAK/MRK Overlapping Kinase

  3. XM_022422388.2 → XP_022278096.1  MAPK/MAK/MRK overlapping kinase isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 177
    PKc_like; Protein Kinases, catalytic domain

  4. XM_022422387.2 → XP_022278095.1  MAPK/MAK/MRK overlapping kinase isoform X3

    UniProtKB/TrEMBL
    A0A8I3RST8
    Conserved Domains (1) summary
    cl21453
    Location:6 → 195
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038596308.1 → XP_038452236.1  MAPK/MAK/MRK overlapping kinase isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 177
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038596311.1 → XP_038452239.1  MAPK/MAK/MRK overlapping kinase isoform X5

    Conserved Domains (1) summary
    cl21453
    Location:1 → 149
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_293061.4 RNA Sequence

Nucleotide Protein
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