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VRK1 VRK serine/threonine kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 490848, updated on 25-Jul-2026
Official Symbol
VRK1provided by VGNC
Official Full Name
VRK serine/threonine kinase 1provided by VGNC
Primary source
VGNC:VGNC:48302
See related
Ensembl:ENSCAFG00845003788 RGD:12219715
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See VRK1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (65718203..65825229)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (64961338..65068324)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (65775210..65882284)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (65390164..65497054)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (65451536..65558390)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097155 Neighboring gene uncharacterized LOC102155533 Neighboring gene uncharacterized LOC119873023 Neighboring gene uncharacterized LOC119873024

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
serine/threonine-protein kinase VRK1
Names
vaccinia related kinase 1
XP_005623842.1
XP_022278072.1
XP_022278073.1
XP_022278074.1
XP_022278075.1
XP_038340098.1
XP_038340099.1
XP_038340100.1
XP_038340101.1
XP_038340102.1
XP_038340103.1
XP_038340104.1
XP_038401608.1
XP_038401609.1
XP_038401610.1
XP_038401611.1
XP_038401612.1
XP_038401613.1
XP_038401614.1
XP_038450891.1
XP_038465708.1
XP_038465709.1
XP_038465710.1
XP_038465711.1
XP_038465712.1
XP_038465713.1
XP_038465714.1
XP_038530521.1
XP_038530522.1
XP_038530523.1
XP_038530524.1
XP_038530525.1
XP_038530526.1
XP_038530527.1
XP_547970.4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    65718203..65825229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674593.1 → XP_038530521.1  serine/threonine-protein kinase VRK1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  2. XM_038674594.1 → XP_038530522.1  serine/threonine-protein kinase VRK1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  3. XM_038674597.1 → XP_038530525.1  serine/threonine-protein kinase VRK1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  4. XM_038674598.1 → XP_038530526.1  serine/threonine-protein kinase VRK1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MQW3, A0A8I3MSH4
    Related
    ENSCAFP00845005379.1, ENSCAFT00845006764.1
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  5. XM_038674595.1 → XP_038530523.1  serine/threonine-protein kinase VRK1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Related
    ENSCAFP00845005389.1, ENSCAFT00845006776.1
    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  6. XM_038674596.1 → XP_038530524.1  serine/threonine-protein kinase VRK1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  7. XM_038674599.1 → XP_038530527.1  serine/threonine-protein kinase VRK1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cl21453
    Location:1 → 271
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    65390164..65497054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484170.1 → XP_038340098.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  2. XM_038484171.1 → XP_038340099.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  3. XM_038484174.1 → XP_038340102.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  4. XM_038484175.1 → XP_038340103.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  5. XM_038484172.1 → XP_038340100.1  

    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  6. XM_038484173.1 → XP_038340101.1  

    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  7. XM_038484176.1 → XP_038340104.1  

    Conserved Domains (1) summary
    cl21453
    Location:1 → 271
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    65451536..65558390
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609781.1 → XP_038465709.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  2. XM_038609780.1 → XP_038465708.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  3. XM_038609784.1 → XP_038465712.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  4. XM_038609785.1 → XP_038465713.1  

    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  5. XM_038609782.1 → XP_038465710.1  

    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  6. XM_038609783.1 → XP_038465711.1  

    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  7. XM_038609786.1 → XP_038465714.1  

    Conserved Domains (1) summary
    cl21453
    Location:1 → 271
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    65775210..65882284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545680.1 → XP_038401608.1  serine/threonine-protein kinase VRK1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  2. XM_038545681.1 → XP_038401609.1  serine/threonine-protein kinase VRK1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  3. XM_038545684.1 → XP_038401612.1  serine/threonine-protein kinase VRK1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  4. XM_038545685.1 → XP_038401613.1  serine/threonine-protein kinase VRK1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MQW3, A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  5. XM_038545682.1 → XP_038401610.1  serine/threonine-protein kinase VRK1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  6. XM_038545683.1 → XP_038401611.1  serine/threonine-protein kinase VRK1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  7. XM_038545686.1 → XP_038401614.1  serine/threonine-protein kinase VRK1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cl21453
    Location:1 → 271
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    64961338..65068324
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022422365.2 → XP_022278073.1  serine/threonine-protein kinase VRK1 isoform X2

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  2. XM_022422364.2 → XP_022278072.1  serine/threonine-protein kinase VRK1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  3. XM_547970.7 → XP_547970.4  serine/threonine-protein kinase VRK1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  4. XM_005623785.4 → XP_005623842.1  serine/threonine-protein kinase VRK1 isoform X5

    UniProtKB/TrEMBL
    A0A8I3MQW3, A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:41 → 341
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  5. XM_022422366.2 → XP_022278074.1  serine/threonine-protein kinase VRK1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  6. XM_038594963.1 → XP_038450891.1  serine/threonine-protein kinase VRK1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cd14122
    Location:26 → 326
    STKc_VRK1; Catalytic domain of the Serine/Threonine protein kinase, Vaccinia Related Kinase 1

  7. XM_022422367.2 → XP_022278075.1  serine/threonine-protein kinase VRK1 isoform X6

    UniProtKB/TrEMBL
    A0A8I3MSH4
    Conserved Domains (1) summary
    cl21453
    Location:1 → 271
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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