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KLHDC1 kelch domain containing 1 [ Canis lupus familiaris (dog) ]

Gene ID: 490677, updated on 25-Jul-2026
Official Symbol
KLHDC1provided by VGNC
Official Full Name
kelch domain containing 1provided by VGNC
Primary source
VGNC:VGNC:42439
See related
Ensembl:ENSCAFG00845002378 RGD:12057711
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See KLHDC1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (26483664..26526463)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (26059799..26102884)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (26530034..26572487)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (26139282..26182087)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (26212874..26255489)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 2 Neighboring gene U1 spliceosomal RNA Neighboring gene DNA polymerase epsilon 2, accessory subunit Neighboring gene kelch domain containing 2 Neighboring gene nuclear export mediator factor Neighboring gene ADP ribosylation factor 6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
kelch domain-containing protein 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    26483664..26526463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038673572.1 → XP_038529500.1  kelch domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02193
    Location:76 → 223
    PLN02193; nitrile-specifier protein
    sd00038
    Location:13 → 101
    Kelch; KELCH repeat [structural motif]
    pfam13418
    Location:255 → 298
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  2. XM_038673574.1 → XP_038529502.1  kelch domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02153
    Location:219 → 353
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  3. XM_038673571.1 → XP_038529499.1  kelch domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02153
    Location:219 → 360
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  4. XM_038673575.1 → XP_038529503.1  kelch domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (3) summary
    PLN02153
    Location:120 → 261
    PLN02153; epithiospecifier protein
    PRK14131
    Location:21 → 151
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:134 → 182
    Kelch; KELCH repeat [structural motif]

  5. XM_038673573.1 → XP_038529501.1  kelch domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L8A2, A0A8C0LBA0, A0A8I3N1W5
    Related
    ENSCAFP00845003352.1, ENSCAFT00845004193.1
    Conserved Domains (3) summary
    PLN02153
    Location:183 → 324
    PLN02153; epithiospecifier protein
    PHA03098
    Location:13 → 162
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:13 → 65
    Kelch; KELCH repeat [structural motif]

RNA

  1. XR_005430971.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    26139282..26182087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038483192.1 → XP_038339120.1  

    Conserved Domains (4) summary
    PLN02193
    Location:76 → 223
    PLN02193; nitrile-specifier protein
    sd00038
    Location:13 → 101
    Kelch; KELCH repeat [structural motif]
    pfam13418
    Location:255 → 298
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  2. XM_038483194.1 → XP_038339122.1  

    Conserved Domains (4) summary
    PLN02153
    Location:219 → 353
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  3. XM_038483191.1 → XP_038339119.1  

    Conserved Domains (4) summary
    PLN02153
    Location:219 → 360
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  4. XM_038483195.1 → XP_038339123.1  

    Conserved Domains (3) summary
    PLN02153
    Location:120 → 261
    PLN02153; epithiospecifier protein
    PRK14131
    Location:21 → 151
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:134 → 182
    Kelch; KELCH repeat [structural motif]

  5. XM_038483193.1 → XP_038339121.1  

    Conserved Domains (3) summary
    PLN02153
    Location:183 → 324
    PLN02153; epithiospecifier protein
    PHA03098
    Location:13 → 162
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:13 → 65
    Kelch; KELCH repeat [structural motif]

RNA

  1. XR_005329346.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    26212874..26255489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608767.1 → XP_038464695.1  

    Conserved Domains (4) summary
    PLN02193
    Location:76 → 223
    PLN02193; nitrile-specifier protein
    sd00038
    Location:13 → 101
    Kelch; KELCH repeat [structural motif]
    pfam13418
    Location:255 → 298
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  2. XM_038608769.1 → XP_038464697.1  

    Conserved Domains (4) summary
    PLN02153
    Location:219 → 353
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  3. XM_038608766.1 → XP_038464694.1  

    Conserved Domains (4) summary
    PLN02153
    Location:219 → 360
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  4. XM_038608770.1 → XP_038464698.1  

    Conserved Domains (3) summary
    PLN02153
    Location:120 → 261
    PLN02153; epithiospecifier protein
    PRK14131
    Location:21 → 151
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:134 → 182
    Kelch; KELCH repeat [structural motif]

  5. XM_038608768.1 → XP_038464696.1  

    Conserved Domains (3) summary
    PLN02153
    Location:183 → 324
    PLN02153; epithiospecifier protein
    PHA03098
    Location:13 → 162
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:13 → 65
    Kelch; KELCH repeat [structural motif]

RNA

  1. XR_005397679.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    26530034..26572487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544643.1 → XP_038400571.1  kelch domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02193
    Location:76 → 223
    PLN02193; nitrile-specifier protein
    sd00038
    Location:13 → 101
    Kelch; KELCH repeat [structural motif]
    pfam13418
    Location:255 → 298
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  2. XM_038544645.1 → XP_038400573.1  kelch domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02153
    Location:219 → 353
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  3. XM_038544642.1 → XP_038400570.1  kelch domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02153
    Location:219 → 360
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  4. XM_038544646.1 → XP_038400574.1  kelch domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (3) summary
    PLN02153
    Location:120 → 261
    PLN02153; epithiospecifier protein
    PRK14131
    Location:21 → 151
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:134 → 182
    Kelch; KELCH repeat [structural motif]

  5. XM_038544644.1 → XP_038400572.1  kelch domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L8A2, A0A8C0LBA0, A0A8I3N1W5
    Conserved Domains (3) summary
    PLN02153
    Location:183 → 324
    PLN02153; epithiospecifier protein
    PHA03098
    Location:13 → 162
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:13 → 65
    Kelch; KELCH repeat [structural motif]

RNA

  1. XR_005363224.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    26059799..26102884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038586577.1 → XP_038442505.1  kelch domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02193
    Location:76 → 223
    PLN02193; nitrile-specifier protein
    sd00038
    Location:13 → 101
    Kelch; KELCH repeat [structural motif]
    pfam13418
    Location:255 → 298
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  2. XM_038586584.1 → XP_038442512.1  kelch domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02153
    Location:219 → 353
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  3. XM_038586572.1 → XP_038442500.1  kelch domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (4) summary
    PLN02153
    Location:219 → 360
    PLN02153; epithiospecifier protein
    PRK14131
    Location:100 → 250
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:106 → 156
    Kelch; KELCH repeat [structural motif]
    pfam13854
    Location:13 → 33
    Kelch_5; Kelch motif

  4. XM_022421980.2 → XP_022277688.1  kelch domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L8A2
    Conserved Domains (3) summary
    PLN02153
    Location:120 → 261
    PLN02153; epithiospecifier protein
    PRK14131
    Location:21 → 151
    PRK14131; N-acetylneuraminate epimerase
    sd00038
    Location:134 → 182
    Kelch; KELCH repeat [structural motif]

  5. XM_547799.7 → XP_547799.2  kelch domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L8A2, A0A8C0LBA0, A0A8I3N1W5
    Conserved Domains (3) summary
    PLN02153
    Location:183 → 324
    PLN02153; epithiospecifier protein
    PHA03098
    Location:13 → 162
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:13 → 65
    Kelch; KELCH repeat [structural motif]

RNA

  1. XR_005385992.1 RNA Sequence

Nucleotide Protein
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