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TC2N tandem C2 domains, nuclear [ Canis lupus familiaris (dog) ]

Gene ID: 490589, updated on 27-Jun-2026
Official Symbol
TC2Nprovided by VGNC
Official Full Name
tandem C2 domains, nuclearprovided by VGNC
Primary source
VGNC:VGNC:47179
See related
Ensembl:ENSCAFG00845019517 RGD:12316185
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
MTAC2D1
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See TC2N in Genome Data Viewer
Location:
chromosome: 8
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (1138284..1209449, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (1108421..1179516, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (1153646..1224733, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (1076424..1147466, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (1032477..1103930, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene cation channel sperm associated auxiliary subunit beta Neighboring gene uncharacterized LOC111096944 Neighboring gene fibulin 5 Neighboring gene uncharacterized LOC119872803

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tandem C2 domains nuclear protein
Names
membrane targeting (tandem) C2 domain containing 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    1138284..1209449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038673039.1 → XP_038528967.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  2. XM_038673041.1 → XP_038528969.1  tandem C2 domains nuclear protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:184 → 286
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:297 → 431
    C2; C2 domain

  3. XM_038673038.1 → XP_038528966.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Related
    ENSCAFP00845026970.1, ENSCAFT00845034437.1
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  4. XM_038673040.1 → XP_038528968.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  5. XM_038673042.1 → XP_038528970.1  tandem C2 domains nuclear protein isoform X3

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:353 → 390
    C2; C2 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    1076424..1147466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038482688.1 → XP_038338616.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  2. XM_038482690.1 → XP_038338618.1  

    Conserved Domains (2) summary
    cd08684
    Location:184 → 286
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:297 → 431
    C2; C2 domain

  3. XM_038482687.1 → XP_038338615.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  4. XM_038482689.1 → XP_038338617.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  5. XM_038482691.1 → XP_038338619.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:353 → 390
    C2; C2 domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    1032477..1103930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038608235.1 → XP_038464163.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  2. XM_038608236.1 → XP_038464164.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  3. XM_038608237.1 → XP_038464165.1  

    Conserved Domains (2) summary
    cd08684
    Location:184 → 286
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:297 → 431
    C2; C2 domain

  4. XM_038608238.1 → XP_038464166.1  

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:353 → 390
    C2; C2 domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    1153646..1224733 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038544109.1 → XP_038400037.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  2. XM_038544111.1 → XP_038400039.1  tandem C2 domains nuclear protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:184 → 286
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:297 → 431
    C2; C2 domain

  3. XM_038544108.1 → XP_038400036.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  4. XM_038544110.1 → XP_038400038.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  5. XM_038544112.1 → XP_038400040.1  tandem C2 domains nuclear protein isoform X3

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:353 → 390
    C2; C2 domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1108421..1179516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022421771.2 → XP_022277479.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  2. XM_038582682.1 → XP_038438610.1  tandem C2 domains nuclear protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:184 → 286
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:297 → 431
    C2; C2 domain

  3. XM_038582657.1 → XP_038438585.1  tandem C2 domains nuclear protein isoform X1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  4. XM_005623156.4 → XP_005623213.1  tandem C2 domains nuclear protein isoform X1

    See identical proteins and their annotated locations for XP_005623213.1

    UniProtKB/TrEMBL
    A0A8C0LBF2, A0A8I3P4S9, A0A8I3P6W7
    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cd08692
    Location:353 → 487
    C2B_Tac2-N; C2 domain second repeat found in Tac2-N (Tandem C2 protein in Nucleus)

  5. XM_038582690.1 → XP_038438618.1  tandem C2 domains nuclear protein isoform X3

    Conserved Domains (2) summary
    cd08684
    Location:240 → 342
    C2A_Tac2-N; C2 domain first repeat found in Tac2-N (Tandem C2 protein in Nucleus)
    cl14603
    Location:353 → 390
    C2; C2 domain
Nucleotide Protein
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