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SYDE2 synapse defective Rho GTPase homolog 2 [ Canis lupus familiaris (dog) ]

Gene ID: 490184, updated on 5-Mar-2024

Summary

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Official Symbol
SYDE2provided by VGNC
Official Full Name
synapse defective Rho GTPase homolog 2provided by VGNC
Primary source
VGNC:VGNC:54074
See related
Ensembl:ENSCAFG00845001161
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (63314310..63362687)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (65422892..65471269)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (63319495..63367884)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (62841461..62889829)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (62811662..62860036)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene BCL10 immune signaling adaptor Neighboring gene chromosome 6 C1orf52 homolog Neighboring gene microtubule-associated protein RP/EB family member 1-like Neighboring gene dynein axonemal intermediate chain 3 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein SYDE2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    63314310..63362687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038667671.1 → XP_038523599.1  rho GTPase-activating protein SYDE2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPV3
    Related
    ENSCAFP00845001559.1, ENSCAFT00845001987.1
    Conserved Domains (2) summary
    cl02570
    Location:911 → 1125
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl14603
    Location:776 → 891
    C2; C2 domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    62841461..62889829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038480381.1 → XP_038336309.1  rho GTPase-activating protein SYDE2 isoform X1

    Conserved Domains (2) summary
    cl02570
    Location:911 → 1125
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl14603
    Location:776 → 891
    C2; C2 domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    62811662..62860036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038602969.1 → XP_038458897.1  rho GTPase-activating protein SYDE2 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    63319495..63367884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038538955.1 → XP_038394883.1  rho GTPase-activating protein SYDE2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0S941, A0A8I3RPQ0, A0A8P0NL45
    Conserved Domains (2) summary
    cl02570
    Location:883 → 1097
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl14603
    Location:748 → 863
    C2; C2 domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    65422892..65471269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535483.1 → XP_038391411.1  rho GTPase-activating protein SYDE2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0S941, A0A8I3RPQ0, A0A8P0NL45
    Conserved Domains (2) summary
    cl02570
    Location:883 → 1097
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl14603
    Location:748 → 863
    C2; C2 domain
Nucleotide Protein
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