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PRSS36 serine protease 36 [ Canis lupus familiaris (dog) ]

Gene ID: 489924, updated on 25-Jul-2026
Official Symbol
PRSS36provided by VGNC
Official Full Name
serine protease 36provided by VGNC
Primary source
VGNC:VGNC:45067
See related
Ensembl:ENSCAFG00845012107 RGD:12239128
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See PRSS36 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (17228763..17238603)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (18672381..18683065)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (17260231..17270035)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (17028146..17038823)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (16947167..16957836)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119872172 Neighboring gene PYD and CARD domain containing Neighboring gene FUS RNA binding protein Neighboring gene serine protease 8 Neighboring gene lysine acetyltransferase 8 Neighboring gene branched chain keto acid dehydrogenase kinase

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
polyserase-2
Names
protease, serine 36

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    17228763..17238603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038670446.1XP_038526374.1  polyserase-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R3G1
    Related
    ENSCAFP00845016935.1, ENSCAFT00845021550.1
    Conserved Domains (2) summary
    cd00190
    Location:2242
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cl21584
    Location:554736
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    17028146..17038823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038477703.1XP_038333631.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    16947167..16957836
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038605850.1XP_038461778.1  

    Conserved Domains (2) summary
    cd00190
    Location:67259
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cl21584
    Location:571753
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    17260231..17270035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038541715.1XP_038397643.1  polyserase-2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R3G1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    18672381..18683065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558444.1XP_038414372.1  polyserase-2 isoform X5

    UniProtKB/TrEMBL
    A0A8I3NK65
    Conserved Domains (2) summary
    cd00190
    Location:67259
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cl21584
    Location:571753
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...