PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PDP2provided by VGNC
Official Full Name: pyruvate dehydrogenase phosphatase catalytic subunit 2provided by VGNC
Primary source: VGNC:VGNC:44389
See related: Ensembl:ENSCAFG00845011036 RGD:12376455
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	5	NC_051809.1 (82858158..82865247, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	5	NC_006587.4 (82410231..82417312, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	5	NC_049226.1 (83007116..83014215, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	5	NC_049265.1 (82681322..82688402, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	5	NC_049746.1 (82368074..82375160, complement)

Chromosome 5 - NC_051809.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cation binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

Names: pyruvate dehyrogenase phosphatase catalytic subunit 2

XP_005620922.1

EC 3.1.3.43

XP_005620923.1

EC 3.1.3.43

XP_022275103.1

EC 3.1.3.43

XP_038333450.1

EC 3.1.3.43

XP_038333451.1

EC 3.1.3.43

XP_038333452.1

EC 3.1.3.43

XP_038333453.1

EC 3.1.3.43

XP_038394672.1

EC 3.1.3.43

XP_038394673.1

EC 3.1.3.43

XP_038394674.1

EC 3.1.3.43

XP_038394675.1

EC 3.1.3.43

XP_038458773.1

EC 3.1.3.43

XP_038458774.1

EC 3.1.3.43

XP_038458775.1

EC 3.1.3.43

XP_038458776.1

EC 3.1.3.43

XP_038523377.1

EC 3.1.3.43

XP_038523378.1

EC 3.1.3.43

XP_038523379.1

EC 3.1.3.43

XP_038523380.1

EC 3.1.3.43

XP_546891.2

EC 3.1.3.43

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051809.1 Reference ROS_Cfam_1.0

Range

82858158..82865247 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038667451.1 → XP_038523379.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038667449.1 → XP_038523377.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Related

ENSCAFP00845015257.1, ENSCAFT00845019509.1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038667450.1 → XP_038523378.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038667452.1 → XP_038523380.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Related

ENSCAFP00845015266.1, ENSCAFT00845019522.1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049265.1 Alternate UMICH_Zoey_3.1

Range

82681322..82688402 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038477524.1 → XP_038333452.1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038477522.1 → XP_038333450.1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038477523.1 → XP_038333451.1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038477525.1 → XP_038333453.1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049746.1 Alternate UNSW_CanFamBas_1.0

Range

82368074..82375160 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049226.1 Alternate UU_Cfam_GSD_1.0

Range

83007116..83014215 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038538746.1 → XP_038394674.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038538744.1 → XP_038394672.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038538745.1 → XP_038394673.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_038538747.1 → XP_038394675.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

82410231..82417312 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005620866.3 → XP_005620923.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

See identical proteins and their annotated locations for XP_005620923.1

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_546891.7 → XP_546891.2 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

See identical proteins and their annotated locations for XP_546891.2

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_005620865.4 → XP_005620922.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

See identical proteins and their annotated locations for XP_005620922.1

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
XM_022419395.2 → XP_022275103.1 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

UniProtKB/TrEMBL

A0A8I3NTB1

Conserved Domains (1) summary

cd00143
Location:111 → 519

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...