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NRCAM neuronal cell adhesion molecule [ Homo sapiens (human) ]

Gene ID: 4897, updated on 1-Jun-2020

Summary

Official Symbol
NRCAMprovided by HGNC
Official Full Name
neuronal cell adhesion moleculeprovided by HGNC
Primary source
HGNC:HGNC:7994
See related
Ensembl:ENSG00000091129 MIM:601581
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 36.1), adrenal (RPKM 15.3) and 5 other tissues See more
Orthologs

Genomic context

See NRCAM in Genome Data Viewer
Location:
7q31.1
Exon count:
47
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (108147626..108456720, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (107788071..108096841, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986835 Neighboring gene laminin subunit beta 4 Neighboring gene uncharacterized LOC105375446 Neighboring gene uncharacterized LOC102724363 Neighboring gene RNA, U7 small nuclear 83 pseudogene Neighboring gene Sharpr-MPRA regulatory region 14594 Neighboring gene patatin like phospholipase domain containing 8 Neighboring gene ribosomal protein L7 pseudogene 32 Neighboring gene THAP domain containing 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche.
NHGRI GWA Catalog
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.
NHGRI GWA Catalog

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Tat tat Microarray analysis indicates HIV-1 Tat-induced upregulation of neuronal cell adhesion molecule (NRCAM) in primary human brain microvascular endothelial cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0343, MGC138845, MGC138846

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ankyrin binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding involved in heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
angiogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
axonal fasciculation NAS
Non-traceable Author Statement
more info
PubMed 
axonogenesis NAS
Non-traceable Author Statement
more info
PubMed 
cell-cell adhesion NAS
Non-traceable Author Statement
more info
PubMed 
central nervous system development NAS
Non-traceable Author Statement
more info
PubMed 
clustering of voltage-gated sodium channels IDA
Inferred from Direct Assay
more info
PubMed 
heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
neuron migration NAS
Non-traceable Author Statement
more info
PubMed 
neuronal action potential propagation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of neuron differentiation NAS
Non-traceable Author Statement
more info
PubMed 
protein localization IEA
Inferred from Electronic Annotation
more info
 
regulation of axon extension NAS
Non-traceable Author Statement
more info
PubMed 
regulation of postsynapse organization IEA
Inferred from Electronic Annotation
more info
 
retinal ganglion cell axon guidance IEA
Inferred from Electronic Annotation
more info
 
synapse assembly TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
axon initial segment ISS
Inferred from Sequence or Structural Similarity
more info
 
external side of plasma membrane NAS
Non-traceable Author Statement
more info
PubMed 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane NAS
Non-traceable Author Statement
more info
PubMed 
integral component of postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection NAS
Non-traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
neuronal cell adhesion molecule
Names
NgCAM-related cell adhesion molecule
neuronal surface protein Bravo

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029898.2 RefSeqGene

    Range
    5321..314092
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001037132.4NP_001032209.1  neuronal cell adhesion molecule isoform A precursor

    See identical proteins and their annotated locations for NP_001032209.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), as well as variant 7, encodes isoform A.
    Source sequence(s)
    AC005058, AC005683, AC007567
    Consensus CDS
    CCDS47686.1
    UniProtKB/Swiss-Prot
    Q92823
    UniProtKB/TrEMBL
    Q14CA1
    Related
    ENSP00000368314.3, ENST00000379028.8
    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11911280
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  2. NM_001193582.1NP_001180511.1  neuronal cell adhesion molecule isoform D precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks two in-frame exons in the coding region, compared to variant 1. The encoded protein (isoform D) is shorter than isoform A. Variants 4 and 12-14 all encode the same isoform (D).
    Source sequence(s)
    AK127035, AK299870, BU735065, BX538010, DA292156
    Consensus CDS
    CCDS75652.1
    UniProtKB/Swiss-Prot
    Q92823
    UniProtKB/TrEMBL
    B7Z670, C9JYY6
    Related
    ENSP00000407858.3, ENST00000413765.6
    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:10981187
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  3. NM_001193583.1NP_001180512.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and lacks three in-frame exons in the coding region, compared to variant 1. The encoded protein (isoform E) is shorter than isoform A. Variants 5 and 15-22 all encode the same isoform (E).
    Source sequence(s)
    AK127035, BC115736, BU735065, BX538010, DA292156
    Consensus CDS
    CCDS55153.1
    UniProtKB/Swiss-Prot
    Q92823
    Related
    ENSP00000368310.4, ENST00000379024.8
    Conserved Domains (9) summary
    cd05868
    Location:356431
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:450513
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:342430
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:829921
    fn3; Fibronectin type III domain
    pfam13882
    Location:10791168
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:269339
    Ig; Immunoglobulin domain
  4. NM_001193584.1NP_001180513.1  neuronal cell adhesion molecule isoform F precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and lacks four in-frame exons in the coding region, compared to variant 1. The encoded protein (isoform F) is shorter than isoform A. Variants 6 and 23 both encode the same isoform (F).
    Source sequence(s)
    AB002341, AK127035, BU735065, BX538010, DA292156
    UniProtKB/Swiss-Prot
    Q92823
    Conserved Domains (9) summary
    cd05868
    Location:356431
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:450513
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:342430
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:829921
    fn3; Fibronectin type III domain
    pfam13882
    Location:10671156
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:269339
    Ig; Immunoglobulin domain
  5. NM_001371119.1NP_001358048.1  neuronal cell adhesion molecule isoform P precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  6. NM_001371122.1NP_001358051.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 5 and 16-22, encodes isoform E.
    Source sequence(s)
    AC005058, AC005683, AC007567
  7. NM_001371123.1NP_001358052.1  neuronal cell adhesion molecule isoform G precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variant 25, encodes isoform G.
    Source sequence(s)
    AC005058, AC005683, AC007567
  8. NM_001371124.1NP_001358053.1  neuronal cell adhesion molecule isoform H precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 27 and 28, encodes isoform H.
    Source sequence(s)
    AC005058, AC005683, AC007567
  9. NM_001371125.1NP_001358054.1  neuronal cell adhesion molecule isoform I

    Status: REVIEWED

    Description
    Transcript Variant: This variant (29), as well as variant 30, encodes isoform I.
    Source sequence(s)
    AC005058, AC005683, AC007567
  10. NM_001371126.1NP_001358055.1  neuronal cell adhesion molecule isoform H precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variants 26 and 28, encodes isoform H.
    Source sequence(s)
    AC005058, AC005683, AC007567
  11. NM_001371127.1NP_001358056.1  neuronal cell adhesion molecule isoform Q precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  12. NM_001371128.1NP_001358057.1  neuronal cell adhesion molecule isoform D precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 4, 13, and 14, encodes isoform D.
    Source sequence(s)
    AC005058, AC005683, AC007567
  13. NM_001371129.1NP_001358058.1  neuronal cell adhesion molecule isoform J precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (31), as well as variant 32, encodes isoform J.
    Source sequence(s)
    AC005058, AC005683, AC007567
  14. NM_001371130.1NP_001358059.1  neuronal cell adhesion molecule isoform K precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (33), as well as variants 34 and 35, encodes isoform K.
    Source sequence(s)
    AC005058, AC005683, AC007567
  15. NM_001371131.1NP_001358060.1  neuronal cell adhesion molecule isoform A precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variant 1, encodes isoform A.
    Source sequence(s)
    AC005058, AC005683, AC007567
  16. NM_001371132.1NP_001358061.1  neuronal cell adhesion molecule isoform J precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (32), as well as variant 31, encodes isoform J.
    Source sequence(s)
    AC005058, AC005683, AC007567
  17. NM_001371133.1NP_001358062.1  neuronal cell adhesion molecule isoform B precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variants 2, 9, 10, and 11, encodes isoform B.
    Source sequence(s)
    AC005058, AC005683, AC007567
  18. NM_001371134.1NP_001358063.1  neuronal cell adhesion molecule isoform R precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  19. NM_001371135.1NP_001358064.1  neuronal cell adhesion molecule isoform S precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  20. NM_001371136.1NP_001358065.1  neuronal cell adhesion molecule isoform T precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  21. NM_001371137.1NP_001358066.1  neuronal cell adhesion molecule isoform U

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  22. NM_001371138.1NP_001358067.1  neuronal cell adhesion molecule isoform V precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  23. NM_001371139.1NP_001358068.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 5, 15, and 17-22, encodes isoform E.
    Source sequence(s)
    AC005058, AC005683, AC007567
  24. NM_001371140.1NP_001358069.1  neuronal cell adhesion molecule isoform W precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  25. NM_001371141.1NP_001358070.1  neuronal cell adhesion molecule isoform X precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  26. NM_001371142.1NP_001358071.1  neuronal cell adhesion molecule isoform Y

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  27. NM_001371143.1NP_001358072.1  neuronal cell adhesion molecule isoform L

    Status: REVIEWED

    Description
    Transcript Variant: This variant (36), as well as variant 37, encodes isoform L.
    Source sequence(s)
    AC005058, AC005683, AC007567
  28. NM_001371144.1NP_001358073.1  neuronal cell adhesion molecule isoform D precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 4, 12, and 14, encodes isoform D.
    Source sequence(s)
    AC005058, AC005683, AC007567
  29. NM_001371145.1NP_001358074.1  neuronal cell adhesion molecule isoform Z precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  30. NM_001371146.1NP_001358075.1  neuronal cell adhesion molecule isoform aa precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  31. NM_001371147.1NP_001358076.1  neuronal cell adhesion molecule isoform I

    Status: REVIEWED

    Description
    Transcript Variant: This variant (30), as well as variant 29, encodes isoform I.
    Source sequence(s)
    AC005058, AC005683, AC007567
  32. NM_001371148.1NP_001358077.1  neuronal cell adhesion molecule isoform M

    Status: REVIEWED

    Description
    Transcript Variant: This variant (38), as well as variants 39 and 40, encodes isoform M.
    Source sequence(s)
    AC005058, AC005683, AC007567
  33. NM_001371149.1NP_001358078.1  neuronal cell adhesion molecule isoform G precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variant 24, encodes isoform G.
    Source sequence(s)
    AC005058, AC005683, AC007567
  34. NM_001371150.1NP_001358079.1  neuronal cell adhesion molecule isoform bb precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  35. NM_001371151.1NP_001358080.1  neuronal cell adhesion molecule isoform B precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 2, 8, 10, and 11, encodes isoform B.
    Source sequence(s)
    AC005058, AC005683, AC007567
  36. NM_001371152.1NP_001358081.1  neuronal cell adhesion molecule isoform K precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (34), as well as variants 33 and 35, encodes isoform K.
    Source sequence(s)
    AC005058, AC005683, AC007567
  37. NM_001371153.1NP_001358082.1  neuronal cell adhesion molecule isoform N precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (41), as well as variant 42, encodes isoform N.
    Source sequence(s)
    AC005058, AC005683, AC007567
  38. NM_001371154.1NP_001358083.1  neuronal cell adhesion molecule isoform O precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (43), as well as variant 44, encodes isoform O.
    Source sequence(s)
    AC005058, AC005683, AC007567
  39. NM_001371155.1NP_001358084.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 5, 15, 16, and 18-22, encodes isoform E.
    Source sequence(s)
    AC005058, AC005683, AC007567
  40. NM_001371156.1NP_001358085.1  neuronal cell adhesion molecule isoform cc precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (58) encodes the longest isoform (cc).
    Source sequence(s)
    AC005058, AC005683, AC007567
  41. NM_001371157.1NP_001358086.1  neuronal cell adhesion molecule isoform dd precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  42. NM_001371158.1NP_001358087.1  neuronal cell adhesion molecule isoform ee precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  43. NM_001371159.1NP_001358088.1  neuronal cell adhesion molecule isoform ll precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  44. NM_001371160.1NP_001358089.1  neuronal cell adhesion molecule isoform ff precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  45. NM_001371161.1NP_001358090.1  neuronal cell adhesion molecule isoform N precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (42), as well as variant 41, encodes isoform N.
    Source sequence(s)
    AC005058, AC005683, AC007567
  46. NM_001371162.1NP_001358091.1  neuronal cell adhesion molecule isoform F precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variant 6, encodes isoform F.
    Source sequence(s)
    AC005058, AC005683, AC007567
  47. NM_001371163.1NP_001358092.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variants 5, 15-17, and 19-22, encodes isoform E.
    Source sequence(s)
    AC005058, AC005683, AC007567
  48. NM_001371164.1NP_001358093.1  neuronal cell adhesion molecule isoform L

    Status: REVIEWED

    Description
    Transcript Variant: This variant (37), as well as variant 36, encodes isoform L.
    Source sequence(s)
    AC005058, AC005683, AC007567
  49. NM_001371165.1NP_001358094.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 5, 15-18, and 20-22, encodes isoform E.
    Source sequence(s)
    AC005058, AC005683, AC007567
  50. NM_001371166.1NP_001358095.1  neuronal cell adhesion molecule isoform O precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (44), as well as variant 43, encodes isoform O.
    Source sequence(s)
    AC005058, AC005683, AC007567
  51. NM_001371167.1NP_001358096.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 5, 15-19, 21, and 22, encodes isoform E.
    Source sequence(s)
    AC005058, AC005683, AC007567
  52. NM_001371168.1NP_001358097.1  neuronal cell adhesion molecule isoform D precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 4, 12, and 13, encodes isoform D.
    Source sequence(s)
    AC005058, AC005683, AC007567
  53. NM_001371169.1NP_001358098.1  neuronal cell adhesion molecule isoform gg precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  54. NM_001371170.1NP_001358099.1  neuronal cell adhesion molecule isoform hh

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  55. NM_001371171.1NP_001358100.1  neuronal cell adhesion molecule isoform B precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 2, 8, 9, and 11, encodes isoform B.
    Source sequence(s)
    AC005058, AC005683, AC007567
  56. NM_001371172.1NP_001358101.1  neuronal cell adhesion molecule isoform H precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28), as well as variants 26 and 27, encodes isoform H.
    Source sequence(s)
    AC005058, AC005683, AC007567
  57. NM_001371173.1NP_001358102.1  neuronal cell adhesion molecule isoform ii precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  58. NM_001371174.1NP_001358103.1  neuronal cell adhesion molecule isoform jj precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  59. NM_001371175.1NP_001358104.1  neuronal cell adhesion molecule isoform kk precursor

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  60. NM_001371176.1NP_001358105.1  neuronal cell adhesion molecule isoform K precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (35), as well as variants 33 and 34, encodes isoform K.
    Source sequence(s)
    AC005683, AC007567
  61. NM_001371177.1NP_001358106.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 5, 15-20, and 22, encodes isoform E.
    Source sequence(s)
    AC005683, AC007567
  62. NM_001371178.1NP_001358107.1  neuronal cell adhesion molecule isoform B precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 2 and 8-10, encodes isoform B.
    Source sequence(s)
    AC005683, AC007567
  63. NM_001371179.1NP_001358108.1  neuronal cell adhesion molecule isoform M

    Status: REVIEWED

    Description
    Transcript Variant: This variant (39), as well as variants 38 and 40, encodes isoform M.
    Source sequence(s)
    AC005683, AC007567
  64. NM_001371180.1NP_001358109.1  neuronal cell adhesion molecule isoform M

    Status: REVIEWED

    Description
    Transcript Variant: This variant (40), as well as variants 38 and 39, encodes isoform M.
    Source sequence(s)
    AC005683, AC007567
  65. NM_001371181.1NP_001358110.1  neuronal cell adhesion molecule isoform E precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 5 and 15-21, encodes isoform E.
    Source sequence(s)
    AC005683, AC007567
  66. NM_001371182.1NP_001358111.1  neuronal cell adhesion molecule isoform mm precursor

    Status: REVIEWED

    Source sequence(s)
    AC005683, AC007567
  67. NM_005010.4NP_005001.3  neuronal cell adhesion molecule isoform B precursor

    See identical proteins and their annotated locations for NP_005001.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks five in-frame exons in the coding region, compared to variant 1. The encoded protein (isoform B) is shorter than isoform A. Variants 2 and 8-11 all encode the same isoform (B).
    Source sequence(s)
    AK127035, BC115736, BU735065, BX538010, DA292156
    Consensus CDS
    CCDS5751.1
    UniProtKB/Swiss-Prot
    Q92823
    Related
    ENSP00000325269.6, ENST00000351718.8
    Conserved Domains (9) summary
    cd05868
    Location:369444
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:463526
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:47129
    IG_like; Immunoglobulin like
    cd00063
    Location:631721
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:355443
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:832924
    fn3; Fibronectin type III domain
    pfam13882
    Location:10701159
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:282352
    Ig; Immunoglobulin domain

RNA

  1. NR_163867.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  2. NR_163868.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  3. NR_163869.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  4. NR_163870.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567
  5. NR_163871.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC005058, AC005683, AC007567

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    108147626..108456720 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011516268.2XP_011514570.1  neuronal cell adhesion molecule isoform X21

    Conserved Domains (8) summary
    cd05868
    Location:279354
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    smart00408
    Location:373436
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:57142
    IG_like; Immunoglobulin like
    cd00063
    Location:551641
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:265353
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:752844
    fn3; Fibronectin type III domain
    pfam13882
    Location:10981191
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:192262
    Ig; Immunoglobulin domain
  2. XM_024446779.1XP_024302547.1  neuronal cell adhesion molecule isoform X41

    Conserved Domains (8) summary
    cd05868
    Location:350425
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    cd00063
    Location:612702
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:9181002
    fn3; Fibronectin type III domain
    pfam13882
    Location:10541143
    Bravo_FIGEY; Bravo-like intracellular region
    pfam13927
    Location:428504
    Ig_3; Immunoglobulin domain
    cl11960
    Location:263333
    Ig; Immunoglobulin domain
    cl28434
    Location:523608
    I-set; Immunoglobulin I-set domain
  3. XM_017012239.2XP_016867728.1  neuronal cell adhesion molecule isoform X13

  4. XM_024446778.1XP_024302546.1  neuronal cell adhesion molecule isoform X40

    Conserved Domains (8) summary
    cd05868
    Location:369444
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    cd00063
    Location:631721
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:9371021
    fn3; Fibronectin type III domain
    pfam13882
    Location:10701163
    Bravo_FIGEY; Bravo-like intracellular region
    pfam13927
    Location:447523
    Ig_3; Immunoglobulin domain
    cl11960
    Location:282352
    Ig; Immunoglobulin domain
    cl28434
    Location:542627
    I-set; Immunoglobulin I-set domain
  5. XM_011516261.2XP_011514563.1  neuronal cell adhesion molecule isoform X9

    Conserved Domains (9) summary
    cd05868
    Location:369444
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:463526
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:47133
    IG_like; Immunoglobulin like
    cd00063
    Location:631721
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:355443
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:832924
    fn3; Fibronectin type III domain
    pfam13882
    Location:11781271
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:282352
    Ig; Immunoglobulin domain
  6. XM_024446777.1XP_024302545.1  neuronal cell adhesion molecule isoform X37

    Conserved Domains (8) summary
    cd05868
    Location:369444
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    cd00063
    Location:641731
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:9471031
    fn3; Fibronectin type III domain
    pfam13882
    Location:10801169
    Bravo_FIGEY; Bravo-like intracellular region
    pfam13927
    Location:447523
    Ig_3; Immunoglobulin domain
    cl11960
    Location:282352
    Ig; Immunoglobulin domain
    cl28434
    Location:542627
    I-set; Immunoglobulin I-set domain
  7. XM_011516257.2XP_011514559.1  neuronal cell adhesion molecule isoform X4

    See identical proteins and their annotated locations for XP_011514559.1

    Conserved Domains (9) summary
    cd05868
    Location:369444
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:463526
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:47133
    IG_like; Immunoglobulin like
    cd00063
    Location:641731
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:355443
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:842934
    fn3; Fibronectin type III domain
    pfam13882
    Location:11881281
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:282352
    Ig; Immunoglobulin domain
  8. XM_017012247.2XP_016867736.1  neuronal cell adhesion molecule isoform X28

  9. XM_024446773.1XP_024302541.1  neuronal cell adhesion molecule isoform X15

    Conserved Domains (8) summary
    cd05868
    Location:356431
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:9341018
    fn3; Fibronectin type III domain
    pfam13882
    Location:11721265
    Bravo_FIGEY; Bravo-like intracellular region
    pfam13927
    Location:434510
    Ig_3; Immunoglobulin domain
    cl11960
    Location:269339
    Ig; Immunoglobulin domain
    cl28434
    Location:529614
    I-set; Immunoglobulin I-set domain
  10. XM_024446775.1XP_024302543.1  neuronal cell adhesion molecule isoform X31

    Conserved Domains (8) summary
    cd05868
    Location:356431
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:9341018
    fn3; Fibronectin type III domain
    pfam13882
    Location:10821175
    Bravo_FIGEY; Bravo-like intracellular region
    pfam13927
    Location:434510
    Ig_3; Immunoglobulin domain
    cl11960
    Location:269339
    Ig; Immunoglobulin domain
    cl28434
    Location:529614
    I-set; Immunoglobulin I-set domain
  11. XM_017012238.2XP_016867727.1  neuronal cell adhesion molecule isoform X12

  12. XM_011516262.2XP_011514564.1  neuronal cell adhesion molecule isoform X11

    Conserved Domains (9) summary
    cd05868
    Location:356431
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:450513
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:342430
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:829921
    fn3; Fibronectin type III domain
    pfam13882
    Location:11751268
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:269339
    Ig; Immunoglobulin domain
  13. XM_017012251.2XP_016867740.1  neuronal cell adhesion molecule isoform X32

  14. XM_017012246.2XP_016867735.1  neuronal cell adhesion molecule isoform X24

  15. XM_017012236.2XP_016867725.1  neuronal cell adhesion molecule isoform X7

  16. XM_017012248.2XP_016867737.1  neuronal cell adhesion molecule isoform X29

  17. XM_011516259.2XP_011514561.1  neuronal cell adhesion molecule isoform X6

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:637727
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:838930
    fn3; Fibronectin type III domain
    pfam13882
    Location:11841277
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  18. XM_006716014.2XP_006716077.1  neuronal cell adhesion molecule isoform X25

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:10861179
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  19. XM_006716007.2XP_006716070.1  neuronal cell adhesion molecule isoform X8

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53135
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11791272
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  20. XM_006716012.2XP_006716075.1  neuronal cell adhesion molecule isoform X20

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:10981191
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  21. XM_006716003.2XP_006716066.1  neuronal cell adhesion molecule isoform X2

    See identical proteins and their annotated locations for XP_006716066.1

    UniProtKB/Swiss-Prot
    Q92823
    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11911284
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  22. XM_011516270.2XP_011514572.1  neuronal cell adhesion molecule isoform X26

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:10891178
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  23. XM_011516269.2XP_011514571.1  neuronal cell adhesion molecule isoform X23

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:10891182
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  24. XM_011516267.2XP_011514569.1  neuronal cell adhesion molecule isoform X19

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11011194
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  25. XM_011516253.2XP_011514555.1  neuronal cell adhesion molecule isoform X1

    See identical proteins and their annotated locations for XP_011514555.1

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11941287
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  26. XM_011516258.1XP_011514560.1  neuronal cell adhesion molecule isoform X4

    See identical proteins and their annotated locations for XP_011514560.1

    Conserved Domains (9) summary
    cd05868
    Location:369444
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:58134
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:463526
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:47133
    IG_like; Immunoglobulin like
    cd00063
    Location:641731
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:355443
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:842934
    fn3; Fibronectin type III domain
    pfam13882
    Location:11881281
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:282352
    Ig; Immunoglobulin domain
  27. XM_011516255.1XP_011514557.1  neuronal cell adhesion molecule isoform X1

    See identical proteins and their annotated locations for XP_011514557.1

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53139
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11941287
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  28. XM_024446780.1XP_024302548.1  neuronal cell adhesion molecule isoform X42

    Conserved Domains (8) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig_NrCAM; Immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:9531037
    fn3; Fibronectin type III domain
    pfam13882
    Location:10861121
    Bravo_FIGEY; Bravo-like intracellular region
    pfam13927
    Location:453529
    Ig_3; Immunoglobulin domain
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
    cl28434
    Location:548633
    I-set; Immunoglobulin I-set domain
  29. XM_011516265.3XP_011514567.1  neuronal cell adhesion molecule isoform X17

    Related
    ENSP00000368308.5, ENST00000379022.8
    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53135
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11941229
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain
  30. XM_011516266.3XP_011514568.1  neuronal cell adhesion molecule isoform X18

    Conserved Domains (9) summary
    cd05868
    Location:375450
    Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
    cd05874
    Location:64140
    Ig6_NrCAM; Sixth immunoglobulin (Ig)-like domain of NrCAM (Ng (neuronglia) CAM-related cell adhesion molecule)
    smart00408
    Location:469532
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:53135
    IG_like; Immunoglobulin like
    cd00063
    Location:647737
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:361449
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:848940
    fn3; Fibronectin type III domain
    pfam13882
    Location:11941229
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:288358
    Ig; Immunoglobulin domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001037133.1: Suppressed sequence

    Description
    NM_001037133.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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