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ACAT1 acetyl-CoA acetyltransferase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 489421, updated on 17-Aug-2024

Summary

Official Symbol
ACAT1provided by VGNC
Official Full Name
acetyl-CoA acetyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:37498
See related
Ensembl:ENSCAFG00845003582
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See ACAT1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (24389926..24409658, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (24286784..24306232, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (24396960..24416675, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (24437216..24456918, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (24338692..24358333, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene ATM serine/threonine kinase Neighboring gene 60S ribosomal protein L31-like Neighboring gene uncharacterized LOC111095856 Neighboring gene nuclear protein, coactivator of histone transcription Neighboring gene uncharacterized LOC111096101 Neighboring gene uncharacterized LOC102156093 Neighboring gene cullin 5

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
acetyl-CoA acetyltransferase, mitochondrial
Names
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
XP_038331079.1
XP_038331081.1
XP_038331082.1
XP_038367601.1
XP_038367610.1
XP_038392211.1
XP_038392212.1
XP_038392213.1
XP_038456410.1
XP_038456411.1
XP_038456412.1
XP_038520938.1
XP_038520939.1
XP_038520940.1
XP_546539.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    24389926..24409658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038665011.1XP_038520939.1  acetyl-CoA acetyltransferase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0K0I4, A0A8C0RN66, A0A8I3MQ37, A0A8I3RSY6, A0A8P0TLF2
    Related
    ENSCAFP00845005080.1, ENSCAFT00845006396.1
    Conserved Domains (1) summary
    cd00751
    Location:43426
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  2. XM_038665012.1XP_038520940.1  acetyl-CoA acetyltransferase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8I3MQ37, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:1336
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  3. XM_038665010.1XP_038520938.1  acetyl-CoA acetyltransferase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0K0D5, A0A8C0YWR8, A0A8I3MQ37, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:49432
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    24437216..24456918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475153.1XP_038331081.1  acetyl-CoA acetyltransferase, mitochondrial isoform X2

    Conserved Domains (1) summary
    cd00751
    Location:43426
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  2. XM_038475154.1XP_038331082.1  acetyl-CoA acetyltransferase, mitochondrial isoform X3

    Conserved Domains (1) summary
    cd00751
    Location:1336
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  3. XM_038475151.1XP_038331079.1  acetyl-CoA acetyltransferase, mitochondrial isoform X1

    Conserved Domains (1) summary
    cd00751
    Location:49432
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    24338692..24358333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600483.1XP_038456411.1  acetyl-CoA acetyltransferase, mitochondrial isoform X2

    Conserved Domains (1) summary
    cd00751
    Location:43426
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  2. XM_038600484.1XP_038456412.1  acetyl-CoA acetyltransferase, mitochondrial isoform X3

    Conserved Domains (1) summary
    cd00751
    Location:1336
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  3. XM_038600482.1XP_038456410.1  acetyl-CoA acetyltransferase, mitochondrial isoform X1

    Conserved Domains (1) summary
    cd00751
    Location:49432
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    24396960..24416675 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038536284.1XP_038392212.1  acetyl-CoA acetyltransferase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0K0I4, A0A8C0RN66, A0A8I3MQ37, A0A8I3RSY6, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:43426
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  2. XM_038536285.1XP_038392213.1  acetyl-CoA acetyltransferase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8I3MQ37, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:1336
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  3. XM_038536283.1XP_038392211.1  acetyl-CoA acetyltransferase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0K0D5, A0A8C0YWR8, A0A8I3MQ37, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:49432
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    24286784..24306232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038511673.1XP_038367601.1  acetyl-CoA acetyltransferase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0K0I4, A0A8C0RN66, A0A8I3MQ37, A0A8I3RSY6, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:43426
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  2. XM_038511682.1XP_038367610.1  acetyl-CoA acetyltransferase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8I3MQ37, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:1336
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
  3. XM_546539.4XP_546539.2  acetyl-CoA acetyltransferase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8C0K0D5, A0A8C0YWR8, A0A8I3MQ37, A0A8P0TLF2
    Conserved Domains (1) summary
    cd00751
    Location:49432
    thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...