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DLAT dihydrolipoamide S-acetyltransferase [ Canis lupus familiaris (dog) ]

Gene ID: 489406, updated on 25-Jul-2026
Official Symbol
DLATprovided by VGNC
Official Full Name
dihydrolipoamide S-acetyltransferaseprovided by VGNC
Primary source
VGNC:VGNC:39974
See related
Ensembl:ENSCAFG00845001723 RGD:12388517
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See DLAT in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (21086208..21117183, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (20985229..21016566, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (21096415..21127748, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (21147724..21178540, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (21047717..21079036, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene NKAP domain containing 1 Neighboring gene PIH1 domain containing 2 Neighboring gene uncharacterized LOC106558799 Neighboring gene DIX domain containing 1 Neighboring gene chromosome 5 C11orf52 homolog Neighboring gene ATP synthase subunit ATP5MPL, mitochondrial-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dihydrolipoyllysine-residue acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in pyruvate decarboxylation to acetyl-CoA IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of pyruvate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Names
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
XP_038330952.1
XP_038392079.1
XP_038456273.1
XP_038520816.1
XP_546524.2

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    21086208..21117183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664888.1 → XP_038520816.1  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JYN1, A0A8C0JZH9, A0A8I3MGU8, A0A8I3MZS6
    Related
    ENSCAFP00845002410.1, ENSCAFT00845003019.1
    Conserved Domains (2) summary
    PRK11892
    Location:96 → 175
    PRK11892; pyruvate dehydrogenase subunit beta; Provisional
    TIGR01349
    Location:221 → 647
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    21147724..21178540 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038475024.1 → XP_038330952.1  

    Conserved Domains (2) summary
    PRK11892
    Location:96 → 175
    PRK11892; pyruvate dehydrogenase subunit beta; Provisional
    TIGR01349
    Location:221 → 647
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    21047717..21079036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600345.1 → XP_038456273.1  

    Conserved Domains (2) summary
    PRK11892
    Location:96 → 175
    PRK11892; pyruvate dehydrogenase subunit beta; Provisional
    TIGR01349
    Location:221 → 647
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    21096415..21127748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038536151.1 → XP_038392079.1  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JYN1, A0A8C0JZH9, A0A8I3MGU8, A0A8I3MZS6
    Conserved Domains (2) summary
    PRK11892
    Location:96 → 175
    PRK11892; pyruvate dehydrogenase subunit beta; Provisional
    TIGR01349
    Location:221 → 647
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    20985229..21016566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546524.7 → XP_546524.2  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0JYN1, A0A8C0JZH9, A0A8I3MGU8, A0A8I3MZS6
    Conserved Domains (2) summary
    PRK11892
    Location:96 → 175
    PRK11892; pyruvate dehydrogenase subunit beta; Provisional
    TIGR01349
    Location:221 → 647
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form
Nucleotide Protein
Heading Accession and Version

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