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VPS11 VPS11 core subunit of CORVET and HOPS complexes [ Canis lupus familiaris (dog) ]

Gene ID: 489374, updated on 17-Aug-2024

Summary

Official Symbol
VPS11provided by VGNC
Official Full Name
VPS11 core subunit of CORVET and HOPS complexesprovided by VGNC
Primary source
VGNC:VGNC:48273
See related
Ensembl:ENSCAFG00845000686
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See VPS11 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (14720316..14730034, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (14829965..14839724, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (14802697..14812441, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (14858298..14868043, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (14762326..14772070, complement)

Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene H2A.X variant histone Neighboring gene hydroxymethylbilane synthase Neighboring gene uncharacterized LOC106558794 Neighboring gene uncharacterized LOC102154262 Neighboring gene hypoxia up-regulated 1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endosome organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in organelle fusion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in vacuole organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in vesicle docking involved in exocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of HOPS complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
vacuolar protein sorting-associated protein 11 homolog
Names
VPS11, CORVET/HOPS core subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051809.1 Reference ROS_Cfam_1.0

    Range
    14720316..14730034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664676.1XP_038520604.1  vacuolar protein sorting-associated protein 11 homolog

    UniProtKB/TrEMBL
    A0A8C0MA69, A0A8I3MLR5, A0A8I3MLU8, A0A8P0TRQ8
    Related
    ENSCAFP00845000878.1, ENSCAFT00845001157.1
    Conserved Domains (4) summary
    cd16688
    Location:820863
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:411536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:864907
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl29593
    Location:142292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049265.1 Alternate UMICH_Zoey_3.1

    Range
    14858298..14868043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474796.1XP_038330724.1  vacuolar protein sorting-associated protein 11 homolog

    Conserved Domains (4) summary
    cd16688
    Location:820863
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:411536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:864907
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl29593
    Location:142292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

    Range
    14762326..14772070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038600138.1XP_038456066.1  vacuolar protein sorting-associated protein 11 homolog

    Conserved Domains (4) summary
    cd16688
    Location:820863
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:411536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:864907
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl29593
    Location:142292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

    Range
    14802697..14812441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535943.1XP_038391871.1  vacuolar protein sorting-associated protein 11 homolog

    UniProtKB/TrEMBL
    A0A8C0MA69, A0A8I3MLR5, A0A8I3MLU8, A0A8P0TRQ8
    Conserved Domains (4) summary
    cd16688
    Location:820863
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:411536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:864907
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl29593
    Location:142292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    14829965..14839724 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546492.7XP_546492.2  vacuolar protein sorting-associated protein 11 homolog

    UniProtKB/TrEMBL
    A0A8C0MA69, A0A8I3MLR5, A0A8I3MLU8, A0A8P0TRQ8
    Conserved Domains (4) summary
    cd16688
    Location:820863
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:411536
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:864907
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl29593
    Location:142292
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...