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HMBS hydroxymethylbilane synthase [ Canis lupus familiaris (dog) ]

Gene ID: 489373, updated on 18-Sep-2020

Summary

Official Symbol
HMBSprovided by VGNC
Official Full Name
hydroxymethylbilane synthaseprovided by VGNC
Primary source
VGNC:VGNC:41704
See related
Ensembl:ENSCAFG00000012342
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs

Genomic context

See HMBS in Genome Data Viewer
Location:
chromosome: 5
Exon count:
18
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 5 NC_006587.3 (14767306..14775205, complement)

Chromosome 5 - NC_006587.3Genomic Context describing neighboring genes Neighboring gene dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Neighboring gene H2A.X variant histone Neighboring gene VPS11 core subunit of CORVET and HOPS complexes Neighboring gene uncharacterized LOC106558794 Neighboring gene uncharacterized LOC102154262

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006587.3 Chromosome 5 Reference CanFam3.1 Primary Assembly

Pathways from PubChem

General protein information

Preferred Names
porphobilinogen deaminase
XP_005619738.1
XP_005619739.1
XP_005619740.1
XP_013968850.1
XP_022273924.1
XP_022273925.1
XP_546491.2

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006587.3 Reference CanFam3.1 Primary Assembly

    Range
    14767306..14775205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022418217.1XP_022273925.1  porphobilinogen deaminase isoform X4

    Conserved Domains (1) summary
    cd13645
    Location:20259
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
  2. XM_546491.6XP_546491.2  porphobilinogen deaminase isoform X1

    Related
    ENSCAFP00000018195.3, ENSCAFT00000019616.3
    Conserved Domains (1) summary
    cd13645
    Location:20299
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
  3. XM_005619682.3XP_005619739.1  porphobilinogen deaminase isoform X2

    See identical proteins and their annotated locations for XP_005619739.1

    Conserved Domains (1) summary
    cd13645
    Location:3282
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
  4. XM_014113375.2XP_013968850.1  porphobilinogen deaminase isoform X5

    Conserved Domains (1) summary
    cd13645
    Location:1244
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
  5. XM_005619683.3XP_005619740.1  porphobilinogen deaminase isoform X2

    See identical proteins and their annotated locations for XP_005619740.1

    Related
    ENSCAFP00000054903.1, ENSCAFT00000068705.1
    Conserved Domains (1) summary
    cd13645
    Location:3282
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
  6. XM_005619681.3XP_005619738.1  porphobilinogen deaminase isoform X2

    See identical proteins and their annotated locations for XP_005619738.1

    Conserved Domains (1) summary
    cd13645
    Location:3282
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
  7. XM_022418216.1XP_022273924.1  porphobilinogen deaminase isoform X3

    Conserved Domains (1) summary
    cd13645
    Location:1259
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
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