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MYO10 myosin X [ Canis lupus familiaris (dog) ]

Gene ID: 489261, updated on 25-Jul-2026
Official Symbol
MYO10provided by VGNC
Official Full Name
myosin Xprovided by VGNC
Primary source
VGNC:VGNC:43554
See related
Ensembl:ENSCAFG00845003406 RGD:12398144
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MYO10 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
42
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (87234383..87429285)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (86115654..86310421)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (87850904..88046417)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (86757648..86953127)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (87010925..87189505)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871654 Neighboring gene uncharacterized LOC111095746 Neighboring gene uncharacterized LOC111095671 Neighboring gene reticulophagy regulator 1 Neighboring gene zinc finger protein 622

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Myosin-X functions in polarized epithelial cells. Liu KC, et al. Mol Biol Cell, 2012 May. PMID 22419816, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
unconventional myosin-X

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    87234383..87429285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038664029.1 → XP_038519957.1  unconventional myosin-X isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2Z1, A0A8I3MV69
    Related
    ENSCAFP00845004816.1, ENSCAFT00845006059.1
    Conserved Domains (12) summary
    smart00015
    Location:741 → 763
    IQ; Calmodulin-binding motif
    smart00139
    Location:1541 → 1687
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1696 → 1950
    B41; Band 4.1 homologues
    cd13202
    Location:1946 → 2034
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1207 → 1308
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1373 → 1498
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:77 → 727
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1689 → 1784
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:875 → 925
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:7 → 58
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:859 → 1009
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1173 → 1215
    PH-like; Pleckstrin homology-like domain

  2. XM_038664028.1 → XP_038519956.1  unconventional myosin-X isoform X2

    UniProtKB/TrEMBL
    A0A8I3MIN4
    Related
    ENSCAFP00845005168.1, ENSCAFT00845006496.1
    Conserved Domains (12) summary
    smart00015
    Location:751 → 773
    IQ; Calmodulin-binding motif
    smart00139
    Location:1551 → 1697
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1706 → 1960
    B41; Band 4.1 homologues
    cd13202
    Location:1956 → 2044
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1217 → 1318
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1383 → 1508
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:87 → 737
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1699 → 1794
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:885 → 935
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:17 → 68
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:869 → 1019
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1183 → 1225
    PH-like; Pleckstrin homology-like domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    86757648..86953127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038474310.1 → XP_038330238.1  

    Conserved Domains (12) summary
    smart00015
    Location:741 → 763
    IQ; Calmodulin-binding motif
    smart00139
    Location:1541 → 1687
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1696 → 1950
    B41; Band 4.1 homologues
    cd13202
    Location:1946 → 2034
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1207 → 1308
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1373 → 1498
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:77 → 727
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1689 → 1784
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:875 → 925
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:7 → 58
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:859 → 1009
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1173 → 1215
    PH-like; Pleckstrin homology-like domain

  2. XM_038474309.1 → XP_038330237.1  

    Conserved Domains (12) summary
    smart00015
    Location:771 → 793
    IQ; Calmodulin-binding motif
    smart00139
    Location:1571 → 1717
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1726 → 1980
    B41; Band 4.1 homologues
    cd13202
    Location:1976 → 2064
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1237 → 1338
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1403 → 1528
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:107 → 757
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1719 → 1814
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:905 → 955
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:37 → 88
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:889 → 1039
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1203 → 1245
    PH-like; Pleckstrin homology-like domain

  3. XM_038474311.1 → XP_038330239.1  

    Conserved Domains (12) summary
    smart00015
    Location:691 → 713
    IQ; Calmodulin-binding motif
    smart00139
    Location:1491 → 1637
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1646 → 1900
    B41; Band 4.1 homologues
    cd13202
    Location:1896 → 1984
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1157 → 1258
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1323 → 1448
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:107 → 674
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1639 → 1734
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:825 → 875
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:37 → 88
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:809 → 959
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1123 → 1165
    PH-like; Pleckstrin homology-like domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    87010925..87189505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599703.1 → XP_038455631.1  

  2. XM_038599702.1 → XP_038455630.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    87850904..88046417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535440.1 → XP_038391368.1  unconventional myosin-X isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2Z1, A0A8I3MV69
    Conserved Domains (12) summary
    smart00015
    Location:741 → 763
    IQ; Calmodulin-binding motif
    smart00139
    Location:1541 → 1687
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1696 → 1950
    B41; Band 4.1 homologues
    cd13202
    Location:1946 → 2034
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1207 → 1308
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1373 → 1498
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:77 → 727
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1689 → 1784
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:875 → 925
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:7 → 58
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:859 → 1009
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1173 → 1215
    PH-like; Pleckstrin homology-like domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    86115654..86310421
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038501286.1 → XP_038357214.1  unconventional myosin-X isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2Z1, A0A8I3MV69
    Conserved Domains (12) summary
    smart00015
    Location:741 → 763
    IQ; Calmodulin-binding motif
    smart00139
    Location:1541 → 1687
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1696 → 1950
    B41; Band 4.1 homologues
    cd13202
    Location:1946 → 2034
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1207 → 1308
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1373 → 1498
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:77 → 727
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1689 → 1784
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:875 → 925
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:7 → 58
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:859 → 1009
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1173 → 1215
    PH-like; Pleckstrin homology-like domain

  2. XM_014113161.3 → XP_013968636.2  unconventional myosin-X isoform X7

    UniProtKB/TrEMBL
    A0A8I3MIN4
    Conserved Domains (12) summary
    smart00015
    Location:771 → 793
    IQ; Calmodulin-binding motif
    smart00139
    Location:1571 → 1717
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1726 → 1980
    B41; Band 4.1 homologues
    cd13202
    Location:1976 → 2064
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1237 → 1338
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1403 → 1528
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:107 → 757
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1719 → 1814
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:905 → 955
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:37 → 88
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:889 → 1039
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1203 → 1245
    PH-like; Pleckstrin homology-like domain

  3. XM_038501294.1 → XP_038357222.1  unconventional myosin-X isoform X9

    UniProtKB/TrEMBL
    A0A8I3MKQ9
    Conserved Domains (12) summary
    smart00015
    Location:691 → 713
    IQ; Calmodulin-binding motif
    smart00139
    Location:1491 → 1637
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1646 → 1900
    B41; Band 4.1 homologues
    cd13202
    Location:1896 → 1984
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1157 → 1258
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1323 → 1448
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:107 → 674
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1639 → 1734
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:825 → 875
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:37 → 88
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:809 → 959
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1123 → 1165
    PH-like; Pleckstrin homology-like domain

  4. XM_038501276.1 → XP_038357204.1  unconventional myosin-X isoform X8

    UniProtKB/TrEMBL
    A0A8I3MIN4
    Conserved Domains (12) summary
    smart00015
    Location:744 → 766
    IQ; Calmodulin-binding motif
    smart00139
    Location:1544 → 1690
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:1699 → 1953
    B41; Band 4.1 homologues
    cd13202
    Location:1949 → 2037
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:1210 → 1311
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:1376 → 1501
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14873
    Location:107 → 730
    MYSc_Myo10; class X myosin, motor domain
    cd17206
    Location:1692 → 1787
    FERM_F1_Myosin-X; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in unconventional myosin-X
    pfam16735
    Location:878 → 928
    MYO10_CC; Unconventional myosin-X coiled coil domain
    pfam18597
    Location:37 → 88
    SH3_19; Myosin X N-terminal SH3 domain
    NF033839
    Location:862 → 1012
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl17171
    Location:1176 → 1218
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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