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HTR4 5-hydroxytryptamine receptor 4 [ Canis lupus familiaris (dog) ]

Gene ID: 489198, updated on 23-Nov-2023

Summary

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Official Symbol
HTR4provided by VGNC
Official Full Name
5-hydroxytryptamine receptor 4provided by VGNC
Primary source
VGNC:VGNC:41831
See related
Ensembl:ENSCAFG00845010692
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See HTR4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (60674206..60843707)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (59949833..60122933)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (61099415..61272556)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (60454461..60627575)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (60581160..60754247)
105 previous assembly CanFam3.1 (GCF_000002285.3) 4 NC_006586.3 (60224534..60359244)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC612325 Neighboring gene adrenoceptor beta 2 Neighboring gene uncharacterized LOC111095720 Neighboring gene F-box protein 38 Neighboring gene sperm-associated acrosin inhibitor-like Neighboring gene ovomucoid-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of appetite IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    60674206..60843707
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663692.1 → XP_038519620.1  5-hydroxytryptamine receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NIS3, A0A8I3RVZ5, A0A8P0T510, A0A8P0T808
    Related
    ENSCAFP00845014726.1, ENSCAFT00845018857.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038663694.1 → XP_038519622.1  5-hydroxytryptamine receptor 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LU90, A0A8C0LZE5, A0A8I3NSA7
    Related
    ENSCAFP00845014833.1, ENSCAFT00845018988.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038663690.1 → XP_038519618.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0RA13, A0A8I3N6U6
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038663693.1 → XP_038519621.1  5-hydroxytryptamine receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0LUB9, A0A8I3N755
    Related
    ENSCAFP00845014988.1, ENSCAFT00845019187.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038663691.1 → XP_038519619.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0RA13, A0A8I3N6U6
    Related
    ENSCAFP00845014855.1, ENSCAFT00845019014.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    60454461..60627575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473990.1 → XP_038329918.1  5-hydroxytryptamine receptor 4 isoform X6

    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038473992.1 → XP_038329920.1  5-hydroxytryptamine receptor 4 isoform X8

    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038473988.1 → XP_038329916.1  5-hydroxytryptamine receptor 4 isoform X5

    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038473991.1 → XP_038329919.1  5-hydroxytryptamine receptor 4 isoform X7

    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038473989.1 → XP_038329917.1  5-hydroxytryptamine receptor 4 isoform X5

    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    60581160..60754247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599382.1 → XP_038455310.1  5-hydroxytryptamine receptor 4 isoform X2

    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038599384.1 → XP_038455312.1  5-hydroxytryptamine receptor 4 isoform X4

    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038599380.1 → XP_038455308.1  5-hydroxytryptamine receptor 4 isoform X1

    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038599383.1 → XP_038455311.1  5-hydroxytryptamine receptor 4 isoform X3

    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038599381.1 → XP_038455309.1  5-hydroxytryptamine receptor 4 isoform X1

    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    61099415..61272556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535086.1 → XP_038391014.1  5-hydroxytryptamine receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NIS3, A0A8I3RVZ5, A0A8P0T510, A0A8P0T808
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038535088.1 → XP_038391016.1  5-hydroxytryptamine receptor 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LU90, A0A8C0LZE5, A0A8I3NSA7
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038535084.1 → XP_038391012.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0RA13, A0A8I3N6U6
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038535087.1 → XP_038391015.1  5-hydroxytryptamine receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0LUB9, A0A8I3N755
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038535085.1 → XP_038391013.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0RA13, A0A8I3N6U6
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    59949833..60122933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038498083.1 → XP_038354011.1  5-hydroxytryptamine receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NIS3, A0A8I3RVZ5, A0A8P0T510, A0A8P0T808
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038498087.1 → XP_038354015.1  5-hydroxytryptamine receptor 4 isoform X4

    UniProtKB/TrEMBL
    A0A8C0LU90, A0A8C0LZE5, A0A8I3NSA7
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038498074.1 → XP_038354002.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0RA13, A0A8I3N6U6
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038498085.1 → XP_038354013.1  5-hydroxytryptamine receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0LUB9, A0A8I3N755
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038498079.1 → XP_038354007.1  5-hydroxytryptamine receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LHU7, A0A8C0RA13, A0A8I3N6U6
    Conserved Domains (1) summary
    cd15056
    Location:20 → 337
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
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