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ARHGEF37 Rho guanine nucleotide exchange factor 37 [ Canis lupus familiaris (dog) ]

Gene ID: 489191, updated on 25-Jul-2026
Official Symbol
ARHGEF37provided by VGNC
Official Full Name
Rho guanine nucleotide exchange factor 37provided by VGNC
Primary source
VGNC:VGNC:38086
See related
Ensembl:ENSCAFG00845009298 RGD:12386304
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See ARHGEF37 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (59840209..59895600, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (59123557..59178961, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (60272603..60327820, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (59627247..59665508, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (59741493..59797047, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106558733 Neighboring gene uncharacterized LOC111095594 Neighboring gene casein kinase 1 alpha 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
rho guanine nucleotide exchange factor 37
XP_038329891.1

Length

  • 675

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    59840209..59895600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663665.1 → XP_038519593.1  rho guanine nucleotide exchange factor 37

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Related
    ENSCAFP00845012748.1, ENSCAFT00845016387.1
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  2. XM_038663664.1 → XP_038519592.1  rho guanine nucleotide exchange factor 37

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  3. XM_038663663.1 → XP_038519591.1  rho guanine nucleotide exchange factor 37

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    59627247..59665508 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473963.1 → XP_038329891.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    59741493..59797047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599354.1 → XP_038455282.1  

    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  2. XM_038599353.1 → XP_038455281.1  

    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  3. XM_038599352.1 → XP_038455280.1  

    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    60272603..60327820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038535057.1 → XP_038390985.1  rho guanine nucleotide exchange factor 37

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  2. XM_038535056.1 → XP_038390984.1  rho guanine nucleotide exchange factor 37

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  3. XM_038535055.1 → XP_038390983.1  rho guanine nucleotide exchange factor 37

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    59123557..59178961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546309.7 → XP_546309.3  rho guanine nucleotide exchange factor 37

    See identical proteins and their annotated locations for XP_546309.3

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  2. XM_005619307.4 → XP_005619364.1  rho guanine nucleotide exchange factor 37

    See identical proteins and their annotated locations for XP_005619364.1

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily

  3. XM_005619308.4 → XP_005619365.1  rho guanine nucleotide exchange factor 37

    See identical proteins and their annotated locations for XP_005619365.1

    UniProtKB/TrEMBL
    A0A8C0LC43, A0A8I3N8C5
    Conserved Domains (4) summary
    cd07589
    Location:263 → 452
    BAR_DNMBP; The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein
    cd11799
    Location:510 → 563
    SH3_ARHGEF37_C1; First C-terminal Src homology 3 domain of Rho guanine nucleotide exchange factor 37
    pfam00621
    Location:34 → 211
    RhoGEF; RhoGEF domain
    cl17036
    Location:611 → 662
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
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