U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

DUSP1 dual specificity phosphatase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 489117, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
DUSP1provided by VGNC
Official Full Name
dual specificity phosphatase 1provided by VGNC
Primary source
VGNC:VGNC:51892
See related
Ensembl:ENSCAFG00845000953
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 4
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (39959081..39962196)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (39532575..39535635)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (40474741..40477792)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (39775072..39778139)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (39964700..39967755)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene endoplasmic reticulum-golgi intermediate compartment 1 Neighboring gene uncharacterized LOC119871507 Neighboring gene uncharacterized LOC111095539 Neighboring gene uncharacterized LOC111095540 Neighboring gene uncharacterized LOC102156464 Neighboring gene uncharacterized LOC111095541 Neighboring gene neuralized E3 ubiquitin protein ligase 1B

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of p38MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
dual specificity protein phosphatase 1
XP_038329593.1
XP_038350778.1
XP_038390673.1
XP_038454974.1
XP_038519276.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    39959081..39962196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663348.1 → XP_038519276.1  dual specificity protein phosphatase 1

    UniProtKB/TrEMBL
    A0A8C0KFR4, A0A8C0M181, A0A8C0RUF7, A0A8I3MDC3
    Related
    ENSCAFP00845001286.1, ENSCAFT00845001627.1
    Conserved Domains (2) summary
    cd01446
    Location:8 → 136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14638
    Location:174 → 324
    DSP_DUSP1; dual specificity phosphatase domain of dual specificity protein phosphatase 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    39775072..39778139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473665.1 → XP_038329593.1  dual specificity protein phosphatase 1

    Conserved Domains (2) summary
    cd01446
    Location:8 → 136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14638
    Location:174 → 324
    DSP_DUSP1; dual specificity phosphatase domain of dual specificity protein phosphatase 1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    39964700..39967755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038599046.1 → XP_038454974.1  dual specificity protein phosphatase 1

    Conserved Domains (2) summary
    cd01446
    Location:8 → 136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14638
    Location:174 → 324
    DSP_DUSP1; dual specificity phosphatase domain of dual specificity protein phosphatase 1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    40474741..40477792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534745.1 → XP_038390673.1  dual specificity protein phosphatase 1

    UniProtKB/TrEMBL
    A0A8C0KFR4, A0A8C0M181, A0A8C0RUF7, A0A8I3MDC3
    Conserved Domains (2) summary
    cd01446
    Location:8 → 136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14638
    Location:174 → 324
    DSP_DUSP1; dual specificity phosphatase domain of dual specificity protein phosphatase 1

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39532575..39535635
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038494850.1 → XP_038350778.1  dual specificity protein phosphatase 1

    UniProtKB/TrEMBL
    A0A8C0KFR4, A0A8C0M181, A0A8C0RUF7, A0A8I3MDC3
    Conserved Domains (2) summary
    cd01446
    Location:8 → 136
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14638
    Location:174 → 324
    DSP_DUSP1; dual specificity phosphatase domain of dual specificity protein phosphatase 1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous