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SAMD8 sterile alpha motif domain containing 8 [ Canis lupus familiaris (dog) ]

Gene ID: 489056, updated on 27-Jun-2026
Official Symbol
SAMD8provided by VGNC
Official Full Name
sterile alpha motif domain containing 8provided by VGNC
Primary source
VGNC:VGNC:45855
See related
Ensembl:ENSCAFG00845010171 RGD:12143903
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See SAMD8 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (25657930..25707475)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (25510520..25559989)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (26109236..26158733)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (25553042..25602565)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (25753678..25803145)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111095493 Neighboring gene dual specificity phosphatase 29 Neighboring gene dual specificity phosphatase 13B Neighboring gene uncharacterized LOC106558706 Neighboring gene uncharacterized LOC111095498 Neighboring gene uncharacterized LOC111095497

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ceramide cholinephosphotransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables sphingomyelin synthase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
sphingomyelin synthase-related protein 1
XP_005619131.2
XP_022273300.1
XP_038329293.1
XP_038329294.1
XP_038329295.1
XP_038329296.1
XP_038348113.1
XP_038390367.1
XP_038390368.1
XP_038390369.1
XP_038390370.1
XP_038454690.1
XP_038454691.1
XP_038454692.1
XP_038454693.1
XP_038518963.1
XP_038518964.1
XP_038518965.1
XP_038518966.1
XP_546174.5

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    25657930..25707475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038663038.1XP_038518966.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  2. XM_038663037.1XP_038518965.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  3. XM_038663036.1XP_038518964.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Related
    ENSCAFP00845013999.1, ENSCAFT00845017971.1
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  4. XM_038663035.1XP_038518963.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    25553042..25602565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473368.1XP_038329296.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  2. XM_038473367.1XP_038329295.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  3. XM_038473366.1XP_038329294.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  4. XM_038473365.1XP_038329293.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    25753678..25803145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598765.1XP_038454693.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  2. XM_038598764.1XP_038454692.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  3. XM_038598763.1XP_038454691.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  4. XM_038598762.1XP_038454690.1  

    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    26109236..26158733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534439.1XP_038390367.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  2. XM_038534442.1XP_038390370.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  3. XM_038534441.1XP_038390369.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  4. XM_038534440.1XP_038390368.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25510520..25559989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546174.6XP_546174.5  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  2. XM_005619074.3XP_005619131.2  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  3. XM_022417592.2XP_022273300.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal
  4. XM_038492185.1XP_038348113.1  sphingomyelin synthase-related protein 1

    UniProtKB/TrEMBL
    A0A8C0KRQ0, A0A8I3N9D4
    Conserved Domains (2) summary
    cd09515
    Location:977
    SAM_SGMS1-like; SAM domain of sphingomyelin synthase related subfamily
    pfam14360
    Location:292365
    PAP2_C; PAP2 superfamily C-terminal