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EGLN1 egl-9 family hypoxia inducible factor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 488971, updated on 25-Jul-2026
Official Symbol
EGLN1provided by VGNC
Official Full Name
egl-9 family hypoxia inducible factor 1provided by VGNC
Primary source
VGNC:VGNC:40240
See related
Ensembl:ENSCAFG00845000514 RGD:12284341
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See EGLN1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (8078966..8136243)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (8045638..8103130)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (8432143..8489997)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (8082361..8139616)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (8204144..8261586)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene DISC1 scaffold protein Neighboring gene uncharacterized LOC111095438 Neighboring gene translin associated factor X Neighboring gene small nucleolar RNA SNORD35 Neighboring gene SprT-like N-terminal domain Neighboring gene exocyst complex component 8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ferrous iron binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptidyl-proline 4-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-proline hydroxylation to 4-hydroxy-L-proline IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
egl nine homolog 1
XP_038328815.1
XP_038328816.1
XP_038344100.1
XP_038389837.1
XP_038454156.1
XP_038518462.1
XP_038518463.1
XP_546089.4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    8078966..8136243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662534.1 → XP_038518462.1  egl nine homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R8V6, A0A8I3MD77
    Related
    ENSCAFP00845000621.1, ENSCAFT00845000828.1
    Conserved Domains (2) summary
    smart00702
    Location:233 → 404
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam01753
    Location:21 → 58
    zf-MYND; MYND finger

  2. XM_038662535.1 → XP_038518463.1  egl nine homolog 1 isoform X2

    Conserved Domains (2) summary
    pfam01753
    Location:21 → 58
    zf-MYND; MYND finger
    cl21496
    Location:233 → 346
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    8082361..8139616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038472887.1 → XP_038328815.1  

  2. XM_038472888.1 → XP_038328816.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    8204144..8261586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598228.1 → XP_038454156.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    8432143..8489997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038533909.1 → XP_038389837.1  egl nine homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0R8V6

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    8045638..8103130
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_546089.6 → XP_546089.4  egl nine homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0R8V6
    Conserved Domains (2) summary
    smart00702
    Location:235 → 406
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam01753
    Location:21 → 58
    zf-MYND; MYND finger

  2. XM_038488172.1 → XP_038344100.1  egl nine homolog 1 isoform X2

    Conserved Domains (2) summary
    pfam01753
    Location:21 → 58
    zf-MYND; MYND finger
    cl21496
    Location:235 → 348
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
Nucleotide Protein
Heading Accession and Version

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