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NR1I3 nuclear receptor subfamily 1 group I member 3 [ Canis lupus familiaris (dog) ]

Gene ID: 488653, updated on 17-Aug-2024

Summary

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Official Symbol
NR1I3provided by VGNC
Official Full Name
nuclear receptor subfamily 1 group I member 3provided by VGNC
Primary source
VGNC:VGNC:43945
See related
Ensembl:ENSCAFG00845029218
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
CAR
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 38
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 38 NC_051842.1 (21370731..21375765)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 38 NC_006620.4 (21327778..21332809)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 38 NC_049259.1 (22082201..22087226)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 38 NC_049298.1 (21267845..21272874)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 38 NC_049779.1 (21673095..21678115)

Chromosome 38 - NC_051842.1Genomic Context describing neighboring genes Neighboring gene myelin protein zero Neighboring gene Purkinje cell protein 4 like 1 Neighboring gene translocase of outer mitochondrial membrane 40 like Neighboring gene apolipoprotein A2 Neighboring gene Fc epsilon receptor Ig

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear receptor and target gene mRNA abundance in duodenum and colon of dogs with chronic enteropathies. Greger DL, et al. Domest Anim Endocrinol, 2006 Nov. PMID 16446074
  2. Nuclear receptor and nuclear receptor target gene messenger ribonucleic acid levels at different sites of the gastrointestinal tract and in liver of healthy dogs. Gropp FN, et al. J Anim Sci, 2006 Oct. PMID 16971569

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear receptor subfamily 1 group I member 3
Names
constitutive androstane receptor NR1I3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051842.1 Reference ROS_Cfam_1.0

    Range
    21370731..21375765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448617.1 → XP_038304545.1  nuclear receptor subfamily 1 group I member 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0JHX6, A0A8C0SJ85, A0A8I3QS93
    Related
    ENSCAFP00845040669.1, ENSCAFT00845051829.1
    Conserved Domains (2) summary
    cd07156
    Location:11 → 82
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:106 → 346
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  2. XM_038448615.1 → XP_038304543.1  nuclear receptor subfamily 1 group I member 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SJ85, A0A8I3QS93
    Related
    ENSCAFP00845040616.1, ENSCAFT00845051767.1
    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 364
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  3. XM_038448616.1 → XP_038304544.1  nuclear receptor subfamily 1 group I member 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 354
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RNA

  1. XR_005308944.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049298.1 Alternate UMICH_Zoey_3.1

    Range
    21267845..21272874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038522501.1 → XP_038378429.1  nuclear receptor subfamily 1 group I member 3 isoform X3

    Conserved Domains (2) summary
    cd07156
    Location:11 → 82
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:106 → 346
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  2. XM_038522499.1 → XP_038378427.1  nuclear receptor subfamily 1 group I member 3 isoform X1

    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 364
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  3. XM_038522500.1 → XP_038378428.1  nuclear receptor subfamily 1 group I member 3 isoform X2

    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 354
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RNA

  1. XR_005351822.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049779.1 Alternate UNSW_CanFamBas_1.0

    Range
    21673095..21678115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038650703.1 → XP_038506631.1  nuclear receptor subfamily 1 group I member 3 isoform X3

  2. XM_038650701.1 → XP_038506629.1  nuclear receptor subfamily 1 group I member 3 isoform X1

  3. XM_038650702.1 → XP_038506630.1  nuclear receptor subfamily 1 group I member 3 isoform X2

RNA

  1. XR_005419573.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049259.1 Alternate UU_Cfam_GSD_1.0

    Range
    22082201..22087226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038586283.1 → XP_038442211.1  nuclear receptor subfamily 1 group I member 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0JHX6, A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:11 → 82
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:106 → 346
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  2. XM_038586281.1 → XP_038442209.1  nuclear receptor subfamily 1 group I member 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 364
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  3. XM_038586282.1 → XP_038442210.1  nuclear receptor subfamily 1 group I member 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 354
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RNA

  1. XR_005385812.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006620.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21327778..21332809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038464163.1 → XP_038320091.1  nuclear receptor subfamily 1 group I member 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0JHX6, A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:11 → 82
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:106 → 346
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  2. XM_038464161.1 → XP_038320089.1  nuclear receptor subfamily 1 group I member 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 364
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  3. XM_038464162.1 → XP_038320090.1  nuclear receptor subfamily 1 group I member 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0SJ85, A0A8I3QS93
    Conserved Domains (2) summary
    cd07156
    Location:29 → 100
    NR_DBD_VDR_like; The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers
    cl11397
    Location:124 → 354
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RNA

  1. XR_005318783.1 RNA Sequence

Nucleotide Protein
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