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SF3B1 splicing factor 3b subunit 1 [ Canis lupus familiaris (dog) ]

Gene ID: 488456, updated on 25-Jul-2026
Official Symbol
SF3B1provided by VGNC
Official Full Name
splicing factor 3b subunit 1provided by VGNC
Primary source
VGNC:VGNC:46069
See related
Ensembl:ENSCAFG00845026632 RGD:12381329
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See SF3B1 in Genome Data Viewer
Location:
chromosome: 37
Exon count:
28
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (6814539..6853018, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (7870202..7908677, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (6803469..6841942, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (6813346..6851824, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (6780170..6818628, complement)

Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 44 Neighboring gene uncharacterized LOC111094396 Neighboring gene proline-rich protein 3-like Neighboring gene uncharacterized LOC119867924 Neighboring gene uncharacterized LOC119867923 Neighboring gene coenzyme Q10B

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in spliceosomal complex assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of U12-type spliceosomal complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of U2 snRNP IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of U2-type prespliceosome IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of catalytic step 2 spliceosome IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
splicing factor 3B subunit 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051841.1 Reference ROS_Cfam_1.0

    Range
    6814539..6853018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038447486.1XP_038303414.1  splicing factor 3B subunit 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QVH3, A0A8I3QBG5
    Related
    ENSCAFP00845036877.1, ENSCAFT00845046996.1
    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461304
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1
  2. XM_038447487.1XP_038303415.1  splicing factor 3B subunit 1 isoform X2

    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461089
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1

RNA

  1. XR_005308255.1 RNA Sequence

    Related
    ENSCAFT00845047215.1
  2. XR_005308254.1 RNA Sequence

    Related
    ENSCAFT00845047342.1
  3. XR_005308256.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049297.1 Alternate UMICH_Zoey_3.1

    Range
    6813346..6851824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038521549.1XP_038377477.1  

    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461304
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1
  2. XM_038521550.1XP_038377478.1  

    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461089
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1

RNA

  1. XR_005351213.1 RNA Sequence

  2. XR_005351212.1 RNA Sequence

  3. XR_005351214.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

    Range
    6780170..6818628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038649652.1XP_038505580.1  

    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461304
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1
  2. XM_038649653.1XP_038505581.1  

    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461089
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1

RNA

  1. XR_005418888.1 RNA Sequence

  2. XR_005418887.1 RNA Sequence

  3. XR_005418889.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

    Range
    6803469..6841942 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038585246.1XP_038441174.1  splicing factor 3B subunit 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QVH3, A0A8I3QBG5
    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461304
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1
  2. XM_038585247.1XP_038441175.1  splicing factor 3B subunit 1 isoform X2

    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461089
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1

RNA

  1. XR_005385165.1 RNA Sequence

  2. XR_005385164.1 RNA Sequence

  3. XR_005385166.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7870202..7908677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_545578.7XP_545578.2  splicing factor 3B subunit 1 isoform X1

    See identical proteins and their annotated locations for XP_545578.2

    UniProtKB/TrEMBL
    A0A8C0QVH3, A0A8I3QBG5
    Conserved Domains (4) summary
    smart01104
    Location:241382
    CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
    COG5181
    Location:4461304
    HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
    sd00044
    Location:850874
    HEAT; HEAT repeat [structural motif]
    pfam08920
    Location:332442
    SF3b1; Splicing factor 3B subunit 1