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CSK C-terminal Src kinase [ Canis lupus familiaris (dog) ]

Gene ID: 487649, updated on 25-Jul-2026
Official Symbol
CSKprovided by VGNC
Official Full Name
C-terminal Src kinaseprovided by VGNC
Primary source
VGNC:VGNC:39661
See related
Ensembl:ENSCAFG00845017685 RGD:12052967
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See CSK in Genome Data Viewer
Location:
chromosome: 30
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (38056541..38074206)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (37784125..37802413)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (38291119..38309429)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (38009325..38027610)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (38055644..38073934)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 1 subfamily A member 1 Neighboring gene cytochrome P450 family 1 subfamily A member 2 Neighboring gene lectin, mannose binding 1 like Neighboring gene complexin 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adherens junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Fc receptor mediated stimulatory signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tyrosine-protein kinase CSK
Names
CSK, non-receptor tyrosine kinase
c-src tyrosine kinase
XP_005638681.1
XP_005638682.1
XP_022268391.1
XP_038298884.1
XP_038298885.1
XP_038298886.1
XP_038373330.1
XP_038373331.1
XP_038373332.1
XP_038373333.1
XP_038436926.1
XP_038436927.1
XP_038436928.1
XP_038436929.1
XP_038501292.1
XP_038501293.1
XP_038501294.1
XP_038501295.1
XP_544774.4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    38056541..38074206
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442956.1 → XP_038298884.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8I3P4Z0
    Related
    ENSCAFP00845024518.1, ENSCAFT00845031318.1
    Conserved Domains (3) summary
    cd05082
    Location:193 → 448
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 180
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  2. XM_038442957.1 → XP_038298885.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8I3P4Z0
    Conserved Domains (3) summary
    cd05082
    Location:193 → 448
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 180
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  3. XM_038442958.1 → XP_038298886.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8I3P4Z0
    Conserved Domains (3) summary
    cd05082
    Location:193 → 448
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 180
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    38009325..38027610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038517402.1 → XP_038373330.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  2. XM_038517403.1 → XP_038373331.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  3. XM_038517404.1 → XP_038373332.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  4. XM_038517405.1 → XP_038373333.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    38055644..38073934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038645364.1 → XP_038501292.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  2. XM_038645365.1 → XP_038501293.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  3. XM_038645366.1 → XP_038501294.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  4. XM_038645367.1 → XP_038501295.1  

    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    38291119..38309429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580998.1 → XP_038436926.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  2. XM_038580999.1 → XP_038436927.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  3. XM_038581000.1 → XP_038436928.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  4. XM_038581001.1 → XP_038436929.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37784125..37802413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544774.7 → XP_544774.4  tyrosine-protein kinase CSK

    See identical proteins and their annotated locations for XP_544774.4

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  2. XM_005638624.4 → XP_005638681.1  tyrosine-protein kinase CSK

    See identical proteins and their annotated locations for XP_005638681.1

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  3. XM_005638625.4 → XP_005638682.1  tyrosine-protein kinase CSK

    See identical proteins and their annotated locations for XP_005638682.1

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase

  4. XM_022412683.2 → XP_022268391.1  tyrosine-protein kinase CSK

    UniProtKB/TrEMBL
    A0A8C0JTF8
    Conserved Domains (3) summary
    cd05082
    Location:188 → 443
    PTKc_Csk; Catalytic domain of the Protein Tyrosine Kinase, C-terminal Src kinase
    cd09937
    Location:78 → 175
    SH2_csk_like; Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk)
    cd11769
    Location:11 → 67
    SH3_CSK; Src Homology 3 domain of C-terminal Src kinase
Nucleotide Protein
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