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GCHFR GTP cyclohydrolase I feedback regulator [ Canis lupus familiaris (dog) ]

Gene ID: 487498, updated on 25-Jul-2026
Official Symbol
GCHFRprovided by VGNC
Official Full Name
GTP cyclohydrolase I feedback regulatorprovided by VGNC
Primary source
VGNC:VGNC:41146
See related
Ensembl:ENSCAFG00845028860 RGD:12317973
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See GCHFR in Genome Data Viewer
Location:
chromosome: 30
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (8027641..8031280)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (7954673..7958306)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (8187169..8190847)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (7951108..7954761)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (8058375..8062002)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene RAD51 recombinase Neighboring gene uncharacterized LOC111093283 Neighboring gene regulator of microtubule dynamics 3 Neighboring gene chromosome 30 C15orf62 homolog Neighboring gene DnaJ heat shock protein family (Hsp40) member C17 Neighboring gene zinc finger FYVE-type containing 19

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP cyclohydrolase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
GTP cyclohydrolase 1 feedback regulatory protein

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    8027641..8031280
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442003.1 → XP_038297931.1  GTP cyclohydrolase 1 feedback regulatory protein

    UniProtKB/TrEMBL
    A0A8C0JY56, A0A8I3PYY2
    Related
    ENSCAFP00845039997.1, ENSCAFT00845051019.1
    Conserved Domains (1) summary
    pfam06399
    Location:3 → 83
    GFRP; GTP cyclohydrolase I feedback regulatory protein (GFRP)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    7951108..7954761
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516493.1 → XP_038372421.1  

    Conserved Domains (1) summary
    pfam06399
    Location:3 → 83
    GFRP; GTP cyclohydrolase I feedback regulatory protein (GFRP)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    8058375..8062002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644365.1 → XP_038500293.1  

    Conserved Domains (1) summary
    pfam06399
    Location:3 → 83
    GFRP; GTP cyclohydrolase I feedback regulatory protein (GFRP)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    8187169..8190847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580084.1 → XP_038436012.1  GTP cyclohydrolase 1 feedback regulatory protein

    UniProtKB/TrEMBL
    A0A8C0JY56, A0A8I3PYY2
    Conserved Domains (1) summary
    pfam06399
    Location:3 → 83
    GFRP; GTP cyclohydrolase I feedback regulatory protein (GFRP)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7954673..7958306
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544622.7 → XP_544622.2  GTP cyclohydrolase 1 feedback regulatory protein

    UniProtKB/TrEMBL
    A0A8C0JY56, A0A8I3PYY2
    Conserved Domains (1) summary
    pfam06399
    Location:3 → 83
    GFRP; GTP cyclohydrolase I feedback regulatory protein (GFRP)
Nucleotide Protein
Heading Accession and Version

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