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DHRS3 dehydrogenase/reductase 3 [ Canis lupus familiaris (dog) ]

Gene ID: 487436, updated on 25-Jul-2026
Official Symbol
DHRS3provided by VGNC
Official Full Name
dehydrogenase/reductase 3provided by VGNC
Primary source
VGNC:VGNC:39934
See related
Ensembl:ENSCAFG00845001328 RGD:12183969
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See DHRS3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (84466959..84505451)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (80360613..80399101)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (83302792..83341302)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (81237580..81276024)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (82236372..82274800)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene arylacetamide deacetylase like 3 Neighboring gene arylacetamide deacetylase like 4 Neighboring gene uncharacterized LOC119870499 Neighboring gene uncharacterized LOC119871139 Neighboring gene basic proline-rich protein-like Neighboring gene uncharacterized LOC111094008 Neighboring gene uncharacterized LOC119870500

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
short-chain dehydrogenase/reductase 3
XP_022270204.2
XP_038320464.1
XP_038320469.1
XP_038327006.1
XP_038327007.1
XP_038327009.1
XP_038327010.1
XP_038387890.1
XP_038387891.1
XP_038387892.1
XP_038387893.1
XP_038452159.1
XP_038452160.1
XP_038452161.1
XP_038452162.1
XP_038516234.1
XP_038516235.1
XP_038516237.1
XP_038516238.1
XP_544561.2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    84466959..84505451
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038660307.1 → XP_038516235.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  2. XM_038660309.1 → XP_038516237.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  3. XM_038660306.1 → XP_038516234.1  short-chain dehydrogenase/reductase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JWX6, A0A8I3MI27
    Related
    ENSCAFP00845001802.1, ENSCAFT00845002276.1
    Conserved Domains (1) summary
    cd05339
    Location:53 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  4. XM_038660310.1 → XP_038516238.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    81237580..81276024
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038471079.1 → XP_038327007.1  

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  2. XM_038471081.1 → XP_038327009.1  

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  3. XM_038471078.1 → XP_038327006.1  

    Conserved Domains (1) summary
    cd05339
    Location:53 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  4. XM_038471082.1 → XP_038327010.1  

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    82236372..82274800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038596232.1 → XP_038452160.1  

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  2. XM_038596233.1 → XP_038452161.1  

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  3. XM_038596231.1 → XP_038452159.1  

    Conserved Domains (1) summary
    cd05339
    Location:53 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  4. XM_038596234.1 → XP_038452162.1  

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    83302792..83341302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038531963.1 → XP_038387891.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  2. XM_038531964.1 → XP_038387892.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  3. XM_038531962.1 → XP_038387890.1  short-chain dehydrogenase/reductase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JWX6, A0A8I3MI27
    Conserved Domains (1) summary
    cd05339
    Location:53 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  4. XM_038531965.1 → XP_038387893.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    80360613..80399101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022414496.2 → XP_022270204.2  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  2. XM_038464536.1 → XP_038320464.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  3. XM_544561.7 → XP_544561.2  short-chain dehydrogenase/reductase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JWX6, A0A8I3MI27
    Conserved Domains (1) summary
    cd05339
    Location:53 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  4. XM_038464541.1 → XP_038320469.1  short-chain dehydrogenase/reductase 3 isoform X2

    Conserved Domains (1) summary
    cd05339
    Location:1 → 196
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
Nucleotide Protein
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