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WDTC1 WD and tetratricopeptide repeats 1 [ Canis lupus familiaris (dog) ]

Gene ID: 487347, updated on 17-Aug-2024

Summary

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Official Symbol
WDTC1provided by VGNC
Official Full Name
WD and tetratricopeptide repeats 1provided by VGNC
Primary source
VGNC:VGNC:48400
See related
Ensembl:ENSCAFG00845010979
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See WDTC1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (73510927..73573894, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (69526269..69589182, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (72344468..72407782, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (70336927..70399877, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (71348425..71404948, complement)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 6 Neighboring gene synaptotagmin like 1 Neighboring gene transmembrane protein 222 Neighboring gene uncharacterized LOC119870386 Neighboring gene 60S ribosomal protein L12-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
WD and tetratricopeptide repeats protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    73510927..73573894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038659722.1 → XP_038515650.1  WD and tetratricopeptide repeats protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N1W5, A0A8I3NHW9
    Conserved Domains (4) summary
    PLN03088
    Location:367 → 437
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:365 → 389
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038659725.1 → XP_038515653.1  WD and tetratricopeptide repeats protein 1 isoform X4

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_038659721.1 → XP_038515649.1  WD and tetratricopeptide repeats protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LCJ7, A0A8C0N1W5, A0A8C0N207, A0A8I3N7M0, A0A8I3NHW9
    Related
    ENSCAFP00845015169.1, ENSCAFT00845019400.1
    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_038659723.1 → XP_038515651.1  WD and tetratricopeptide repeats protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N1W5, A0A8I3NHW9
    Conserved Domains (5) summary
    smart00320
    Location:562 → 601
    WD40; WD40 repeats
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    70336927..70399877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038470575.1 → XP_038326503.1  WD and tetratricopeptide repeats protein 1 isoform X2

    Conserved Domains (4) summary
    PLN03088
    Location:367 → 437
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:365 → 389
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038470578.1 → XP_038326506.1  WD and tetratricopeptide repeats protein 1 isoform X4

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_038470574.1 → XP_038326502.1  WD and tetratricopeptide repeats protein 1 isoform X1

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_038470577.1 → XP_038326505.1  WD and tetratricopeptide repeats protein 1 isoform X3

    Conserved Domains (5) summary
    smart00320
    Location:562 → 601
    WD40; WD40 repeats
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    71348425..71404948 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038595641.1 → XP_038451569.1  WD and tetratricopeptide repeats protein 1 isoform X2

    Conserved Domains (4) summary
    PLN03088
    Location:367 → 437
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:365 → 389
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038595643.1 → XP_038451571.1  WD and tetratricopeptide repeats protein 1 isoform X4

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_038595640.1 → XP_038451568.1  WD and tetratricopeptide repeats protein 1 isoform X1

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_038595642.1 → XP_038451570.1  WD and tetratricopeptide repeats protein 1 isoform X3

    Conserved Domains (5) summary
    smart00320
    Location:562 → 601
    WD40; WD40 repeats
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    72344468..72407782 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038531419.1 → XP_038387347.1  WD and tetratricopeptide repeats protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N1W5, A0A8I3NHW9
    Conserved Domains (4) summary
    PLN03088
    Location:367 → 437
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:365 → 389
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_038531421.1 → XP_038387349.1  WD and tetratricopeptide repeats protein 1 isoform X4

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_038531418.1 → XP_038387346.1  WD and tetratricopeptide repeats protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LCJ7, A0A8C0N1W5, A0A8C0N207, A0A8I3N7M0, A0A8I3NHW9
    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_038531420.1 → XP_038387348.1  WD and tetratricopeptide repeats protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N1W5, A0A8I3NHW9
    Conserved Domains (5) summary
    smart00320
    Location:562 → 601
    WD40; WD40 repeats
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    69526269..69589182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544473.6 → XP_544473.3  WD and tetratricopeptide repeats protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0N1W5, A0A8I3NHW9
    Conserved Domains (4) summary
    PLN03088
    Location:367 → 437
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:365 → 389
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_005617722.3 → XP_005617779.1  WD and tetratricopeptide repeats protein 1 isoform X4

    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_005617721.3 → XP_005617778.1  WD and tetratricopeptide repeats protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LCJ7, A0A8C0N1W5, A0A8C0N207, A0A8I3N7M0, A0A8I3NHW9
    Conserved Domains (4) summary
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_022412719.1 → XP_022268427.1  WD and tetratricopeptide repeats protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N1W5, A0A8I3NHW9
    Conserved Domains (5) summary
    smart00320
    Location:562 → 601
    WD40; WD40 repeats
    PLN03088
    Location:368 → 438
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:366 → 390
    TPR; TPR repeat [structural motif]
    sd00039
    Location:51 → 88
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:34 → 163
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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