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WASF2 WASP family member 2 [ Canis lupus familiaris (dog) ]

Gene ID: 487343, updated on 27-Jun-2026
Official Symbol
WASF2provided by VGNC
Official Full Name
WASP family member 2provided by VGNC
Primary source
VGNC:VGNC:48334
See related
Ensembl:ENSCAFG00845010413 RGD:12297356
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See WASF2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (73362170..73435297)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (69377973..69450865)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (72196025..72269045)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (70188441..70261511)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (71199742..71272857)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene FGR proto-oncogene, Src family tyrosine kinase Neighboring gene AT-hook DNA binding motif containing 1 Neighboring gene uncharacterized LOC111093304 Neighboring gene G protein-coupled receptor 3 Neighboring gene CD164 molecule like 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Arp2/3 complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase A regulatory subunit binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Arp2/3 complex-mediated actin nucleation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
wiskott-Aldrich syndrome protein family member 2
Names
WAS protein family member 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    73362170..73435297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038659711.1 → XP_038515639.1  wiskott-Aldrich syndrome protein family member 2

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  2. XM_038659709.1 → XP_038515637.1  wiskott-Aldrich syndrome protein family member 2

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Related
    ENSCAFP00845014310.1, ENSCAFT00845018334.1
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  3. XM_038659710.1 → XP_038515638.1  wiskott-Aldrich syndrome protein family member 2

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Related
    ENSCAFP00845014399.1, ENSCAFT00845018447.1
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    70188441..70261511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038470564.1 → XP_038326492.1  

    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  2. XM_038470562.1 → XP_038326490.1  

    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  3. XM_038470563.1 → XP_038326491.1  

    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    71199742..71272857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038595630.1 → XP_038451558.1  

    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  2. XM_038595628.1 → XP_038451556.1  

    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  3. XM_038595629.1 → XP_038451557.1  

    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    72196025..72269045
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038531408.1 → XP_038387336.1  wiskott-Aldrich syndrome protein family member 2

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  2. XM_038531406.1 → XP_038387334.1  wiskott-Aldrich syndrome protein family member 2

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  3. XM_038531407.1 → XP_038387335.1  wiskott-Aldrich syndrome protein family member 2

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    69377973..69450865
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_544469.7 → XP_544469.1  wiskott-Aldrich syndrome protein family member 2

    See identical proteins and their annotated locations for XP_544469.1

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  2. XM_005617713.4 → XP_005617770.1  wiskott-Aldrich syndrome protein family member 2

    See identical proteins and their annotated locations for XP_005617770.1

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

  3. XM_005617714.4 → XP_005617771.1  wiskott-Aldrich syndrome protein family member 2

    See identical proteins and their annotated locations for XP_005617771.1

    UniProtKB/TrEMBL
    A0A8I3NA73, A0A8I3RVS9
    Conserved Domains (2) summary
    cd21762
    Location:450 → 453
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:428 → 479
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins
Nucleotide Protein
Heading Accession and Version

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